Idiopathic pulmonary fibrosis
Scarring throughout the lungs without an identifiable cause. Symptoms of pulmonary fibrosis include shortness of breath, coughing and diminished exercise tolerance. The treatment involves corticosteroids (such as Prednisone) and/or other medications that suppress the body's immune system. Interferon gamma-1b treatment for 12 months was reported to improve the status of idiopathic pulmonary fibrosis patients who did not respond to corticosteroid therapy, according to a report in The New England Journal of Medicine (Ziesche R et al. N Engl J Med 1999;341:1264-1269; and an accompanying editorial by du Bois RM N Engl J Med 1999;341:1302-1304.). The goal of treatment is to decrease lung inflammation and subsequent scarring. Responses to treatment are variable. Toxicity and side effects of treatments can be serious. Therefore, patients with pulmonary fibrosis should be followed by a lung specialist experienced with this condition. Pulmonary fibrosis can cause hypoxia (decreased oxygen in the blood) and this can lead to elevated pressure in the pulmonary artery (pulmonary hypertension) and this can in turn lead to failure of the right ventricle of the heart. Therefore, patients are frequently also treated with supplemental oxygen to prevent pulmonary hypertension.

* * *

chronic inflammation and progressive fibrosis of the pulmonary alveolar walls, with steadily progressive dyspnea, resulting finally in death from oxygen lack or right heart failure. Sometimes it is a component of bronchiolitis obliterans with organizing pneumonia (see under bronchiolitis).The acute, rapidly fatal form is called acute interstitial pneumonia or Hamman-Rich syndrome. Called also chronic fibrous pneumonia, interstitial or usual interstitial pneumonia, diffuse interstitial pulmonary f., fibrosing alveolitis, and interstitial or interstitial pulmonary f.

Medical dictionary. 2011.

Look at other dictionaries:

  • Idiopathic pulmonary fibrosis — Classification and external resources Extensive lung fibrosis from usual interstitial pneumonitis ICD 10 J …   Wikipedia

  • Pulmonary fibrosis — Scarring throughout the lungs which can be caused by many conditions such as, sarcoidosis, hypersensitivity pneumonitis, asbestosis, and certain medications. Chronic pulmonary inflammation and fibrosis can also occur without an identifiable cause …   Medical dictionary

  • pulmonary fibrosis — ▪ pathology       end result of a variety of inflammatory diseases of the lungs (lung) in which dense fibrous connective tissue replaces lung tissue. The fibrous tissue stiffens the lungs, reduces space available for inhaled air, and interferes… …   Universalium

  • Idiopathic pulmonary haemosiderosis — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 29717 ICD10 = ICD9 = ICD9|516.1 ICDO = OMIM = 178550 MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = Idiopathic pulmonary haemosiderosis is a condition affecting the lungs which… …   Wikipedia

  • diffuse interstitial pulmonary fibrosis — idiopathic pulmonary f …   Medical dictionary

  • Idiopathic interstitial pneumonia — Classification and external resources Micrograph of usual interstitial pneumonia (UIP). UIP is the most common pattern of idiopathic interstitial pneumonia and usually represents idiopathic pulmonary fibrosis …   Wikipedia

  • Pulmonary hypertension — Pulmonary arterial hypertension Classification and external resources The pulmonary artery receives blood (blue arrow) from the right ventricle of the heart; increased pressure on the artery can impair the function of the right ventricle ICD …   Wikipedia

  • Pulmonary embolism — Classification and external resources Chest spiral CT scan with radiocontrast agent showing multiple filling defects both at the bifurcation and in the pulmonary arteries. ICD 10 …   Wikipedia

  • Pulmonary edema — Classification and external resources Pulmonary edema with small pleural effusions on both sides. ICD 10 J …   Wikipedia

  • Pulmonary consolidation — Classification and external resources Pneumonia as seen on chest x ray. A: Normal chest x ray. B: Abnormal chest x ray with consolidation from pneumonia in the right lung, middle or inferior lobe (white area, left side of image) …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”