retinoid

retinoid
1. Resembling a resin; resinous. [G. retine, resin, + eidos, resemblance] 2. Resembling the retina. [Mediev. L. retina] 3. In plural form, term used to describe the natural forms and synthetic analogs of retinol.

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ret·i·noid 'ret-ən-.ȯid n any of various synthetic or naturally occurring analogs of vitamin A
retinoid adj

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n.
any one of a group of drugs derived from vitamin A. They bind to one or more of six specific receptors that are found on many cells. On the skin they act to cause drying and peeling and a reduction in oil (sebum) production. These effects can be useful in the treatment of severe acne, psoriasis, ichthyosis, and other skin disorders. Retinoids include isotretinoin, tretinoin, acitretin, and tazarotene; they are administered by mouth or applied as a cream. Possible side-effects, which may be serious, include severe fetal abnormalities (if taken by pregnant women), toxic effects on babies (if taken by breastfeeding mothers), liver and kidney damage, excessive drying, redness and itching of the skin, and muscle pain and stiffness.

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ret·i·noid (retґĭ-noid) 1. resembling the retina. 2. retinol, retinal, or any structurally similar natural derivative or synthetic compound; the latter need any not have vitamin A activity.

Medical dictionary. 2011.

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  • Retinoid — Ret i*noid, a. [Gr. ??? resin + oid.] Resinlike, or resinform; resembling a resin without being such. [1913 Webster] …   The Collaborative International Dictionary of English

  • retinoid — [ret′ n oid΄] n. any of a large class of natural or synthetic, photosensitive chemical compounds that are similar to vitamin A, including retinoic acid and retinal …   English World dictionary

  • Retinoid — The retinoids are a class of chemical compounds that are related chemically to vitamin A. Retinoids are used in medicine, primarily due to the way they regulate epithelial cell growth. Retinoids have many important and diverse functions… …   Wikipedia

  • Retinoid — Retinoide sind chemische Substanzen, die in ihrer chemischen Struktur oder in ihrer biologischen Aktivität verwandt mit dem Retinol (Vitamin A) sind. [1] Inhaltsverzeichnis 1 Definitionsgeschichte 2 Therapeutisch eingesetzte Retinoide 2.1 Nicht… …   Deutsch Wikipedia

  • Retinoid X receptor alpha — Retinoid X receptor, alpha PDB rendering based on 1by4 …   Wikipedia

  • Retinoid X receptor gamma — Retinoid X receptor, gamma Crystallographic structure of the DNA binding domain of the Retinoid X receptor, gamma. PDB rendering based on 1by4 …   Wikipedia

  • Retinoid X receptor beta — Retinoid X receptor, beta PDB rendering based on 1by4 …   Wikipedia

  • Retinoid receptor — Retinoid receptors are nuclear receptors (a class of proteins) that bind to retinoids. When bound to a retinoid, they act as transcription factors, altering the expression of genes with corresponding response elements.Subtypes include: * Retinoic …   Wikipedia

  • Retinoid x receptor — Retinoid X receptor, ou RXR, est une protéine de la famille des récepteurs nucléaires ligand dépendant activé par son association avec le récepteur de l acide rétinoïque (ou vitamine A). Sommaire 1 Structure 2 Mécanisme d action 3 Fonctions …   Wikipédia en Français

  • Retinoid-related orphan receptor — (pour récepteur orphelin apparenté au récepteur des rétinoïdes), ou ROR, est une protéine de la famille des récepteurs nucléaires dont le ligand n est à ce jour pas clairement identifié. Sommaire 1 Structure 2 Mécanisme d action 3 Fonctions …   Wikipédia en Français

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