Interleukin-3
A protein that stimulates the immune system to develop mast cells and bone-marrow cells. Abbreviated IL-3.
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A cytokine derived from activated CD4+ lymphocytes, fibroblasts, and endothelial cells that increases production of monocytes. It acts in hematopoiesis by controlling production and differentiation of granulocytes. SYN: multicolony-stimulating factor.

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interleukin-3 -'thrē n an interleukin that is a colony-stimulating factor produced esp. by T cells stimulated by mitogen or antigen and that promotes the proliferation and differentiation of various stem cells (as hematopoietic stem cells)

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(IL-3) a lymphokine produced by antigen- or mitogen-activated T lymphocytes, which stimulates proliferation of hematopoietic as well as lymphoid stem cells; a colony-stimulating factor for all bone marrow progenitor cells. IL-3 supports the growth and differentiation of early hematopoietic and lymphoid stem cells as well as that of more mature hematopoietic cells, including granulocytes, macrophages, and mast cells.

Medical dictionary. 2011.

Look at other dictionaries:

  • Interleukin 3 — (colony stimulating factor, multiple), also known as IL3, is a human gene.cite web | title = Entrez Gene: IL3 interleukin 3 (colony stimulating factor, multiple)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Interleukin-3 — Dieser Artikel oder Abschnitt bedarf einer Überarbeitung. Näheres ist auf der Diskussionsseite angegeben. Hilf mit, ihn zu verbessern, und entferne anschließend diese Markierung. Interleukine (IL x) sind zu den Zytokinen zählende Peptidhormone, d …   Deutsch Wikipedia

  • Interleukin 3 — Dieser Artikel oder Abschnitt bedarf einer Überarbeitung. Näheres ist auf der Diskussionsseite angegeben. Hilf mit, ihn zu verbessern, und entferne anschließend diese Markierung. Interleukine (IL x) sind zu den Zytokinen zählende Peptidhormone, d …   Deutsch Wikipedia

  • interleukin 3 — Immunol. a lymphokine protein, secreted by T cells, that participates in the regulation of blood cell production. Abbr.: IL 3 [1980 85; see INTERLEUKIN 1] * * * …   Universalium

  • interleukin 3 — Immunol. a lymphokine protein, secreted by T cells, that participates in the regulation of blood cell production. Abbr.: IL 3 [1980 85; see INTERLEUKIN 1] …   Useful english dictionary

  • interleukin-3 — in·ter·leu·kin 3 (ĭnʹtər lo͞o kĭn thrēʹ) n. Abbr. IL 3 A lymphokine, released by helper T cells in response to an antigen or mitogen, that stimulates the growth of blood stem cells and lymphoid cells such as macrophages and mast cells. * * * …   Universalium

  • interleukin-3 — IL 3. A type of biological response modifier (a substance that can improve the body s natural response to infection and disease) that enhances the immune system s ability to fight tumor cells. These substances are normally produced by the body.… …   English dictionary of cancer terms

  • interleukin-3 — (= IL 3) Product of mitogen activated T cells: colony stimulating factor for bone marrow stem cells and mast cells …   Dictionary of molecular biology

  • Interleukin-3 receptor — protein Name= interleukin 3 receptor, alpha caption= width= HGNCid= 6012 Symbol= IL3RA AltSymbols= CD123 EntrezGene= OMIM=308385 RefSeq= UniProt= PDB= ECnumber= Chromosome=X Arm=p Band=22.3 LocusSupplementaryData=protein Name=interleukin 3… …   Wikipedia

  • Interleukin 5 receptor alpha subunit — Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin 5 receptor. IL5RA also denotes its human gene.cite web | title = Entrez Gene: IL5RA interleukin 5 receptor, alpha| url =… …   Wikipedia

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