site

site
A place or location or locus. SYN: situs. [L. situs]
- acceptor s. the ribosomal binding s. for the aminoacyl-tRNA during protein synthesis.
- acceptor splicing s. SYN: right splicing junction.
- active s. that portion of an enzyme molecule at which the actual reaction proceeds; considered to consist of one or more residues or atoms in a spatial arrangement that permits interaction with the substrate to effect the reaction of the latter.
- allosteric s. postulated as the place on an enzyme, other than the active s., where a compound, which may be the ultimate product of the biosynthetic pathway involving the enzyme, may bind and influence the activity of the enzyme by changing the enzyme's conformation; the influence of CTP on aspartate carbamoyltransferase activity exemplifies the concept of an allosteric s. on an allosteric protein.
- antibody-combining s. SYN: paratope.
- antigen-binding s. SYN: paratope.
- cleavage s. SYN: restriction s..
- fragile s. [MIM*136540, MIM*136670] a nonstaining gap at a specific point on a chromosome, usually involving both chromatids, always at the same point on chromosomes of different cells from an individual or kindred; it results in in vitro production of acentric fragments, deleted chromosomes, or other chromosome anomalies; inherited as a dominant chromosome marker.
- immunologically privileged sites sites where allografts are not readily rejected or tumors escape immune surveillance probably because these particular areas have poor lymphatic drainage and are not readily accessible to effector cells of the immune system.
- ligand-binding s. the s. on a protein's surface that binds a ligand; equivalent to the active s. if the ligand is the substrate of an enzyme.
- privileged s. an anatomic area lacking lymphatic drainage, such as the brain, cornea, and hamster cheek pouch, in which heterologous tumors may grow because the host does not become sensitized.
- receptor s. point of attachment for viruses, hormones, or other activators to cell membranes.
- replication s. the in vivo s. on DNA of DNA replication.
- restriction s. a s. in nucleic acid in which the bordering bases are of such a type as to leave them vulnerable to the cleaving action of an endonuclease. SYN: cleavage s..
- sequence-tagged sites (STSs) short stretches of DNA sequences that can be detected by use of the polymerase chain reaction.
- switching s. the break point in a DNA sequence at which a gene segment unites with another gene segment, as in the production of the immunoglobulins.

* * *

site 'sīt n the place, scene, or point of something <the \site of inflammation> see active site

* * *

(sīt) a place, position, or locus.

Medical dictionary. 2011.

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  • site — [ sit ] n. m. • 1576, par l it. sito « place, position » 1302; du lat. situs 1 ♦ Paysage (considéré du point de vue de l esthétique, du pittoresque). Site grandiose. « Cette colonnade inscrit le sanctuaire juste comme il faut dans le site qui lui …   Encyclopédie Universelle

  • Site R — ist eine weitgehend geheime unterirdische Einrichtung der US amerikanischen Regierung im Berg Raven Rock in Pennsylvania, der sich etwa 14 km östlich von Waynesboro und rund 10 km nord nordöstlich von Camp David befindet. Heutige Funktionen… …   Deutsch Wikipedia

  • Site — Site, n. [L. situs, fr. sinere, situm, to let, p. p. situs placed, lying, situate: cf. F. site. Cf. {Position}.] 1. The place where anything is fixed; situation; local position; as, the site of a city or of a house. Chaucer. [1913 Webster] 2. A… …   The Collaborative International Dictionary of English

  • Site — 〈[ saıt] f. 10; EDV〉 Bildschirmseite (im Internet) (WebSite) [engl., eigtl. „Stelle, Stätte“] * * * Site [sa̮it ], die; , s [engl. site, ↑ Website] (EDV): Kurzf. von ↑ Website. * * * SITE   [saɪ …   Universal-Lexikon

  • site — m. site. Site arquelogic, site oèb : site archéologique ; site web …   Diccionari Personau e Evolutiu

  • site — [sīt] n. [ME < L situs, position, situation < pp. of sinere, to put down, permit, allow < IE base * sei , to cast out, let fall: see SIDE] 1. a piece of land considered from the standpoint of its use for some specified purpose [a good… …   English World dictionary

  • site — (izg. sȃjt) m <N mn ovi> DEFINICIJA inform. skup svih web stranica povezanih u cjelinu (vizualno i sadržajno) (npr. www.hrvatski turizam.hr) [modni site; site Ministarstva znanosti i tehnologije]; stranica ETIMOLOGIJA engl …   Hrvatski jezični portal

  • site — [pron. SAIT] s. n. spaţiu în care sunt situate informaţii pe reţeaua de internet. (< engl. site) Trimis de raduborza, 16.03.2009. Sursa: MDN …   Dicționar Român

  • Site — 〈 [saıt] f.; Gen.: , Pl.: s; EDV〉 Bildschirmseite (im Internet); WebSite [Etym.: engl., eigtl. »Stelle, Stätte«] …   Lexikalische Deutsches Wörterbuch

  • Site — [ sait, engl. sʌit] die; , s <aus engl. site »Standort, Stelle«> Kurzform von ↑Website …   Das große Fremdwörterbuch

  • site — place or position occupied by something, late 14c., from Anglo Fr. site, from L. situs place, position, from si , root of sinere let, leave alone, permit …   Etymology dictionary

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