Iris, speckled
Due to little white (or lightly colored) spots that are slightly elevated on the surface of the iris. These spots, arranged in a ring concentric with the pupil, occur in normal children but are far more frequent in Down’s syndrome (trisomy 21). They were described in 1924 by Thomas Brushfield, are called Brushfield’s spots, and are due to aggregation of a normal iris element (connective tissue).

Medical dictionary. 2011.

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  • Speckled iris — Due to little white (or lightly colored) spots that are slightly elevated on the surface of the iris. These spots, arranged in a ring concentric with the pupil, occur in normal children but are far more frequent in Down’s syndrome (trisomy 21).… …   Medical dictionary

  • Brushfield’s spots — Speckled iris. Little white spots that slightly elevated on the surface of the iris arranged in a ring concentric with the pupil. These spots occur in normal children but are far more frequent in Down’s syndrome (trisomy 21). They were described… …   Medical dictionary

  • Spots, Brushfield’s — Speckled iris. Little white spots that slightly elevated on the surface of the iris and are arranged in a ring concentric with the pupil. These spots occur in normal children but are far more frequent in Down’s syndrome (trisomy 21). They were… …   Medical dictionary

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