Klinefelter syndrome
A chromosome condition in boys and men that is usually due to their having 47 chromosomes with XXY sex chromosomes, rather than having the usual 46 chromosomes with XY sex chromosomes. XXY is one of the most common chromosomal abnormalities. It occurs in 1 in 500 male births. Because it is so common, Klinefelter syndrome is considered one the SCVs (sex chromosome variations). The signs of Klinefelter syndrome include small testes, insufficient production of testosterone, and infertility. XXY males are more likely than other males to show breast enlargement, lack of facial and body hair, a rounded body type, to be overweight, and be taller than their fathers and brothers. The diagnosis can be difficult to make in early childhood. Klinefelter boys tend to have learning and/or behavioral problems more often than other boys. In 1942 Drs. Harry F Klinefelter, EC Reifenstein, Jr and their mentor Fuller Albright at the Massachusetts General Hospital in Boston published a report about 9 men who had enlarged breasts, sparse facial and body hair, small testes, and inability to produce sperm. This combination of features has come to be recognized as Klinefelter syndrome. For much more information, see Klinefelter syndrome.

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Kline·fel·ter syndrome (klīnґfel-tər) [Harry Fitch Klinefelter, Jr., American physician, 1912–1990] see under syndrome.

Medical dictionary. 2011.

Look at other dictionaries:

  • Klinefelter syndrome — Klinefelter syndrome. См. синдром Клайнфельтера. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Klinefelter syndrome — Chromosomal disorder that occurs in one out of 500 males. With an extra X chromosome in each cell (XXY), patients look male, with firm, small testes, but they produce no sperm and may have enlarged breasts and buttocks and very long legs.… …   Universalium

  • Klinefelter syndrome — A genetic disorder in males caused by having one or more extra X chromosomes. Males with this disorder may have larger than normal breasts, a lack of facial and body hair, a rounded body type, and small testicles. They may learn to speak much… …   English dictionary of cancer terms

  • Klinefelter syndrome — noun syndrome in males that is characterized by small testes and long legs and enlarged breasts and reduced sperm production and mental retardation; a genetic defect in which an extra X chromosome (XXY) is present in the male • Syn: ↑Klinefelter… …   Useful english dictionary

  • Klinefelter syndrome — noun see Klinefelter s syndrome …   New Collegiate Dictionary

  • Klinefelter syndrome — noun A genetic condition in which a male is born with two X chromosome …   Wiktionary

  • Klinefelter syndrome —  Not felter’s. Genetic disease that causes language difficulties …   Bryson’s dictionary for writers and editors

  • Klinefelter syndrome — affecting genitalia and internal ducts, usually male; testes underdeveloped and do not produce sperm …   Eponyms, nicknames, and geographical games

  • chromatin-negative Klinefelter syndrome — chromatin negative Klinefelter syndrome. См. хроматин отрицательный синдром Клайнфельтера. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Klinefelter's syndrome — Infobox Disease ICD10 = ICD10|Q|98|0|q|90 ICD10|Q|98|4|q|90 ICD9 = ICD9|758.7 Caption = 47,XXY ICDO = OMIM = MedlinePlus = eMedicineSubj = ped eMedicineTopic = 1252 MeshID = D007713 Klinefelter s syndrome, 47,XXY or XXY syndrome is a condition… …   Wikipedia

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