- Angioid streaks
- Tiny breaks in the elastin-filled tissue in the back of the eye (retinae). These abnormalities are visible to the doctor during an examination using a viewing instrument called an ophthalmoscope. Angioid streaks are seen in patients with pseudoxanthoma elasticum (abbreviated PXE), a rare disorder of degeneration of the elastic fibers with tiny areas of calcification in the skin, back of the eyes (retinae), and blood vessels. Angioid streaks can be associated with blindness.
* * *reddish to dark-brown irregular streaks radiating outwards from the optic disc underneath the retinal vessels. They represent irregular linear cracks in Bruch's membrane and can be the site for the development of new vessels from the choroid that leak. They are seen in such systemic conditions as pseudoxanthoma elasticum, Paget's disease, and sickle-cell anaemia.
* * *red to black irregular bands observed in the ocular fundus running outward from the region of the optic disk, which are seen in certain conditions, including pseudoxanthoma elasticum, osteitis deformans, and sickle-cell anemia. The lesions are thought to represent ruptures in the lamina basalis of the choroid.
Angioid streaks (arrows) in Ehlers-Danlos syndrome.
Medical dictionary. 2011.