- A malignant tumor of smooth muscle origin. Smooth muscle is the major structural component of most hollow internal organs and the walls of blood vessels. Can occur almost anywhere in the body but is most frequent in the uterus and gastrointestinal tract. Complete surgical excision, if possible, is the treatment of choice.
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* * *leio·myo·sar·co·ma .lī-ō-.mī-ō-sär-'kō-mə n, pl -mas also -ma·ta -mət-ə a sarcoma composed in part of smooth muscle cells
* * *n.a malignant tumour of smooth muscle, most commonly found in the uterus, stomach, small bowel, and at the base of the bladder. It is the second most common sarcoma of soft tissues. This tumour is rare in children, occurring most commonly in the bladder, prostate, and stomach.
* * *leio·myo·sar·co·ma (li″o-mi″o-sahr-koґmə) [leio- + myosarcoma] a sarcoma containing large spindle cells of smooth muscle, most commonly of the uterus, retroperitoneal region, or extremities.
Medical dictionary. 2011.