Leukemoid reaction

Leukemoid reaction
A benign condition in which the high number of white blood cells found in a blood test resembles the numbers seen in leukemia. For example, infectious mononucleosis can return blood-test results with a leukemoid reaction.
* * *
A moderate, advanced, or sometimes extreme degree of leukocytosis in the circulating blood, similar to that occurring in various forms of leukemia, but not the result of leukemic disease; usually, there is a disproportionate increase in the number of forms (including immature stages) in one series of leukocytes, and various examples of myelocytic, lymphocytic, monocytic, or plasmocytic l. may be also indistinguishable from leukocytosis that is associated with certain forms of leukemia. Leukemoid reactions are sometimes observed as a feature of: 1) infectious disease caused by certain bacteria and other biologic agents, e.g., tuberculosis, diphtheria, and chickenpox; 2) intoxication of various types, e.g., eclampsia, serious burns, and mustard gas poisoning; 3) malignant neoplasms, e.g., carcinoma of the colon, of the lung, of the kidney, or of other organs; 4) acute hemorrhage or hemolysis.
- lymphocytic l. leukocytosis of varying degree, with adult lymphocytes and immature forms amounting to 40% (or more) of the total number of white blood cells in the circulating blood; may be observed in association with pertussis, infectious mononucleosis, gonorrhea, chickenpox, and sarcoidosis.
- monocytic l. leukocytosis of varying degree, e.g., 30,000–40,000/mm3, with adult monocytes and immature forms amounting to 30% (or more) of the total number of white blood cells in the circulating blood; may be observed in association with tuberculosis, especially the first infection, miliary type.
- myelocytic l. leukocytosis of at least moderate degree, e.g., 50,000 or more per mm3, with a few immature forms, e.g., 1 or 2% myelocytes, but chiefly mature polymorphonuclear leukocytes in the circulating blood; may be observed in association with tuberculosis, chronic osteomyelitis, various types of empyema, malaria, pneumococcal pneumonia, meningococcal meningitis, Hodgkin disease, and metastases of carcinoma in the bone marrow.
- plasmocytic l. the presence of unusual numbers of plasma cells, i.e., plasmocytosis, in the bone marrow; may be observed in association with sarcoidosis, rheumatoid arthritis, cirrhosis, Hodgkin disease, and certain of the so-called vascular collagen diseases.

Medical dictionary. 2011.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • Leukemoid reaction — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 30101 ICD10 = ICD10|D|72|8|d|70 ICD9 = ICD9|288.62 ICDO = OMIM = MedlinePlus = 000575 eMedicineSubj = eMedicineTopic = MeshID = D007955The term leukemoid reaction, also referred to as… …   Wikipedia

  • leukemoid — Resembling leukemia in various signs and symptoms, especially with reference to changes in the circulating blood. SEE ALSO: l. reaction. [leukemia + G. eidos, resemblance] * * * leu·ke·moid or chiefly Brit leu·kae·moid lü kē mȯid adj resembling… …   Medical dictionary

  • leukemoid — lüˈkēˌmȯid adjective Etymology: leukemia + oid : resembling leukemia but not involving the same changes in the blood forming organs a leukemoid reaction in malaria …   Useful english dictionary

  • congenital leukemoid reaction — transient myeloproliferative disorder …   Medical dictionary

  • reaction — 1. The response of a muscle or other living tissue or organism to a stimulus. 2. The color change effected in litmus and certain other organic pigments by contact with substances such as acids or alkalies; also the property that such substances… …   Medical dictionary

  • leukemic reaction — leukemoid reaction a peripheral blood picture resembling that of leukemia or indistinguishable from it on the basis of morphologic appearance alone, with leukocytosis of varying degrees and increased numbers of immature cells in circulation. It… …   Medical dictionary

  • Chronic myelogenous leukemia — Classification and external resources The Philadelphia chromosome as seen by metaphase FISH. ICD 10 C92.1 …   Wikipedia

  • Alkaline phosphatase — (ALP) (EC number|3.1.3.1) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is called dephosphorylation . As… …   Wikipedia

  • List of cutaneous conditions — This is an incomplete list, which may never be able to satisfy particular standards for completeness. You can help by expanding it with reliably sourced entries. See also: Cutaneous conditions, Category:Cutaneous conditions, and ICD 10… …   Wikipedia

  • Leukocytosis — DiseaseDisorder infobox Name = Leukocytosis ICD10 = ICD10|D|72|8|d|70 ICD9 = ICD9|288.3, ICD9|288.6x Caption = ICDO = OMIM = DiseasesDB = 33024 MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = D007964 Leukocytosis is a raised white blood… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”