Multifactorial inheritance
The type of hereditary pattern seen when there is more than one genetic factor involved and, sometimes, when there are also environmental factors participating in the causation of a condition. Many common traits are multifactorial. Skin color, for example, is multifactorially determined. So is height and so also is intelligence. The most common diseases tend also to multifactorial. Type 2 diabetes, the most common type of diabetes, is multifactorial. It is due to the inheritance of susceptibility genes (genes that make one susceptible to developing diabetes) plus environmental factors such as obesity. Obesity, in turn, clearly is multifactorial in causation.

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inheritance determined by multiple factors, genetic and possibly nongenetic (environmental), each with only a partial effect. See also polygenic i.

Medical dictionary. 2011.

Look at other dictionaries:

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  • Multifactorial — Multiple factors. Multifactorial inheritance is the type of hereditary pattern seen when there is more than one genetic factor involved and, sometimes, when there are also environmental factors participating in the causation of a condition. Many… …   Medical dictionary

  • Inheritance — Not something that is contained in a will, but rather a gene, chromosome or genome that is transmitted from parent to child. The pattern of inheritance is the manner in which a gene is transmitted. For example, the pattern of inheritance may be… …   Medical dictionary

  • multifactorial — adjective Date: 1920 1. having characters or a mode of inheritance dependent on a number of genes at different loci 2. (or multifactor) having, involving, or produced by a variety of elements or causes • multifactorially adverb …   New Collegiate Dictionary

  • complex inheritance — multifactorial i …   Medical dictionary

  • polygenic inheritance — quantitative inheritance inheritance determined by many genes at different loci, with small additive effects. See also multifactorial i …   Medical dictionary

  • Quantitative trait locus — See also: Epistasis Quantitative traits refer to phenotypes (characteristics) that vary in degree and can be attributed to polygenic effects, i.e., product of two or more genes, and their environment. Quantitative trait loci (QTLs) are stretches… …   Wikipedia

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