Multiple myeloma
A malignancy of plasma cells (a form of lymphocyte) that typically involves multiple sites within the bone morrow and secretes all

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multiple myeloma n a disease of bone marrow that is characterized by the presence of numerous myelomas in various bones of the body called also myelomatosis

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a disseminated type of plasma cell dyscrasia characterized by multiple bone marrow tumor foci and secretion of an M component, associated with widespread osteolytic lesions resulting in bone pain, pathologic fractures, hypercalcemia, and normochromic normocytic anemia; spread to extraosseous sites occurs frequently in advanced disease. Depression of immunoglobulin levels results in increased susceptibility to infection. Bence Jones proteinuria is present in many cases and may result in systemic amyloidosis. Renal failure from calcium nephropathy or extensive cast formation may also occur. Called also plasma cell m. See also myeloma cell, under cell.

Multiple myeloma in bone marrow, showing large plasma cells with nucleoli.


Medical dictionary. 2011.

Look at other dictionaries:

  • Multiple myeloma — Classification and external resources Micrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H E stain ICD …   Wikipedia

  • multiple myeloma — multiple myeloma. См. болезнь Рустицкого Калера. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • multiple myeloma — Pathol. a malignant plasma cell tumor of the bone marrow that destroys bone tissue. [1895 1900; MYEL + OMA] * * * ▪ pathology also called  plasma cell myeloma  or  myelomatosis        malignant proliferation (tumour) of cells within the bone… …   Universalium

  • multiple myeloma — noun myeloma that develops in several places at the same time • Hypernyms: ↑myeloma * * * noun : a disease of bone marrow characterized by the presence of numerous myelomas in various bones of the body * * * Pathol. a malignant plasma cell tumor… …   Useful english dictionary

  • multiple myeloma — myeloma …   The new mediacal dictionary

  • multiple myeloma — See myeloma cell …   Dictionary of molecular biology

  • multiple myeloma — noun A cancer of the white blood cells. Syn: myelomatosis, plasma cell myeloma, Kahlers disease …   Wiktionary

  • multiple myeloma — A type of cancer that begins in plasma cells (white blood cells that produce antibodies). Also called Kahler’s disease, myelomatosis, or plasma cell myeloma …   English dictionary of cancer terms

  • multiple myeloma — noun Date: 1897 a disease of bone marrow that is characterized by the presence of numerous myelomas in various bones of the body …   New Collegiate Dictionary

  • multiple myeloma — mul′tiple myelo′ma n. pat a malignant plasma cell tumor of the bone marrow that destroys bone tissue • Etymology: 1895–1900 …   From formal English to slang

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