Multiple symmetric lipomatosis
A disorder characterized by painless symmetrical diffuse deposits of fat beneath the skin of the neck, upper trunk, arms and legs. The condition is thought to be genetic although its exact mode of inheritance is uncertain. It may be a mitochondrial DNA disease. It frequently appears in association with alcoholic liver disease, macrocytic anemia ("low blood" with big red blood cells) and peripheral neuropathy (disease of the peripheral nervous system, as opposed to the brain and spinal cord). The peripheral neuropathy has often been laid to alcoholism, but the neuropathy is likely an integral part of the syndrome. This disorder affects mainly men and is more frequent in the Mediterranean area. It has been suggested that the distribution of fat in multiple symmetric lipomatosis resembles that of a pre-Roman (6th century BC) Italic statue called the Capestrano warrior discovered in the Abruzzi region of Italy. Multiple symmetric lipomatosis is also known as cephalothoracic lipodystrophy, the Launois-Bensaude syndrome and Madelung disease. It was called 'fat neck' (Fetthals) by Madelung in 1888.

* * *

nodular circumscribed lipomatosis in which the fat deposits merge to form a ring around the neck; called also Madelung disease or neck.

Medical dictionary. 2011.

Look at other dictionaries:

  • Lipomatosis, multiple symmetric — A disorder characterized by painless symmetrical diffuse deposits of fat beneath the skin of the neck, upper trunk, arms and legs. The condition is thought to be genetic although its exact mode of inheritance is uncertain. It may be a… …   Medical dictionary

  • Symmetric lipomatosis, multiple — A disorder characterized by painless symmetrical diffuse deposits of fat beneath the skin of the neck, upper trunk, arms and legs. The condition is thought to be genetic although its exact mode of inheritance is uncertain. It may be a… …   Medical dictionary

  • benign symmetric lipomatosis — multiple symmetric l …   Medical dictionary

  • Lipomatosis simétrica múltiple — Psciente afectado por lipomatosis simétrica múltiple Clasificación y recursos externos …   Wikipedia Español

  • lipomatosis — SYN: adiposis. encephalocraniocutaneous l. a rare syndrome of multiple fibrolipomas or angiofibromas of the face, scalp, and neck present at birth, sometimes with symptomatic intracranial lipomas. mediastinal l …   Medical dictionary

  • nodular circumscribed lipomatosis — formation of multiple circumscribed or encapsulated lipomas in subcutaneous tissue. When these are distributed symmetrically around the neck, the condition is called multiple symmetric lipomatosis or Madelung disease. A variety in which the… …   Medical dictionary

  • lipoma annulare colli — multiple symmetric lipomatosis …   Medical dictionary

  • Madelung neck — multiple symmetric lipomatosis …   Medical dictionary

  • syndrome — The aggregate of symptoms and signs associated with any morbid process, and constituting together the picture of the disease. SEE ALSO: disease. [G. s., a running together, tumultuous concourse; (in med.) a concurrence of symptoms, fr. syn,… …   Medical dictionary

  • Otto Wilhelm Madelung — (May 15, 1846, Gotha July 22, 1926, Göttingen) was a German surgeon who was a native of Gotha. In 1869 he received his medical doctorate from the University of Tübingen, and later worked in a military hospital during the Franco Prussian War.… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”