C2

prostatic tumor with extracapsular extension and positive margins [Jewett staging system]; second cervical nerve; second cervical vertebra; second component of complement; second concept [UMLS]; tumor with metastases to lymph nodes and extension into perirectal adipose tissue

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a component of the classical complement pathway that binds surface-bound C4b; cleavage of C2 by C1s releases a small C2b fragment and leaves C2a bound to C4b to form the classic pathway C3 convertase (C4b,2a).