Nolvadex (tamoxifen)
An antiestrogen (a drug that blocks the effects of estrogen) which competes with estrogen for binding sites in target tissues such as breast. Tamoxifen has been widely publicized. It was approved by the US Food and Drug Administration (FDA) to treat breast cancer and help prevent it in women at high risk for the disease and, then in 2000, to treat women who have had surgery and radiation for ductal carcinoma in situ (DCIS) to lower the risk of invasive breast cancer arising from the intraductal carcinoma.

Medical dictionary. 2011.

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  • Tamoxifen — Systematic (IUPAC) name (Z …   Wikipedia

  • Tamoxifen — Ta*mox i*fen (t[a^]*m[o^]k s[i^]*f[e^]n), n. a chemical compound ({C26H29NO}) which is non steroidal but physiogically active as an estrogen antagonist. It is used to treat postmenopausal breast cancer. Chemically it is 1 p… …   The Collaborative International Dictionary of English

  • Nolvadex — Strukturformel Allgemeines Freiname Tamoxifen Ande …   Deutsch Wikipedia

  • Tamoxifen — Strukturformel Allgemeines Freiname Tamoxifen …   Deutsch Wikipedia

  • tamoxifen — /teuh mok seuh feuhn, fen /, n. Pharm. an antineoplastic drug, C26H29NO, that blocks the estrogen receptors on cancer cells, used in the treatment of breast cancer. [1970 75; perh. T(RANS) + AM(INO) + OXY 2 + PHEN(YL), with resp. of y and ph] * * …   Universalium

  • Nolvadex — A drug used to treat certain types of breast cancer in women and men. It is also used to prevent breast cancer in women who have had ductal carcinoma in situ (abnormal cells in the ducts of the breast) and are at a high risk of developing breast… …   English dictionary of cancer terms

  • tamoxifen — ta·mox·i·fen ta mäk si .fen n a selective estrogen receptor modulator that acts as an estrogen antagonist in breast tissue and is administered orally in the form of its citrate C26H29NO·C6H8O7 esp. to treat breast cancer see NOLVADEX * * * n. a… …   Medical dictionary

  • tamoxifen — A drug used to treat certain types of breast cancer in women and men. It is also used to prevent breast cancer in women who have had ductal carcinoma in situ (abnormal cells in the ducts of the breast) and are at a high risk of developing breast… …   English dictionary of cancer terms

  • tamoxifen citrate — A drug used to treat certain types of breast cancer in women and men. It is also used to prevent breast cancer in women who have had ductal carcinoma in situ (abnormal cells in the ducts of the breast) and are at a high risk of developing breast… …   English dictionary of cancer terms

  • Nolvadex — Nol·va·dex näl və .deks trademark used for a preparation of the citrate of tamoxifen * * * Nol·va·dex (nolґvə deks″) trademark for a preparation of tamoxifen citrate …   Medical dictionary

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