DNASE

DNASE
deoxyribo-nuclease

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DN·ase (')dē-'en-.ās, -.āz also DNA·ase (.)dē-.en-'ā-.ās, -.āz n DEOXYRIBONUCLEASE

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n.
an enzyme that catalyses the cleavage of DNA. A genetically engineered form, recombinant human DNAse (dornase alfa), is used in the treatment of cystic fibrosis to reduce the viscosity of the sticky secretions in the lungs. Administered by inhalation via a jet nebulizer, it appears to hydrolyse extracellular DNA that accumulates with other neutrophil debris in the airways. Trade name: Pulmozyme.

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deoxyribonuclease.

Medical dictionary. 2011.

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Look at other dictionaries:

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  • DNase — [Kurzw. aus ↑ DNA u. ↑ ase], die; , n: svw. ↑ Desoxyribonuklease …   Universal-Lexikon

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  • DNase — Désoxyribonucléase La désoxyribonucléase, ou DNAse est une enzyme catalysant les acides désoxyribonucléiques en nucléotides ou polynucléotides. Elle hydrolyse les liaisons phosphodiester. Prenons le cas de la DNase I : cette endonucléase… …   Wikipédia en Français

  • DNAse — deoxyribo nuclease * * * DN·ase ( )dē en .ās, .āz also DNA·ase (.)dē .en ā .ās, .āz n DEOXYRIBONUCLEASE * * * n. an enzyme that catalyses the cleavage of DNA. A genetically engineered form, recombinant human DNAse (dornase alfa), is used in the… …   Medical dictionary

  • DNase — deoxyribo nuclease * * * DN·ase ( )dē en .ās, .āz also DNA·ase (.)dē .en ā .ās, .āz n DEOXYRIBONUCLEASE * * * n. an enzyme that catalyses the cleavage of DNA. A genetically engineered form, recombinant human DNAse (dornase alfa), is used in the… …   Medical dictionary

  • DNAse — n. an enzyme that catalyses the cleavage of DNA. A genetically engineered form, recombinant human DNAse (dornase alfa), is used in the treatment of cystic fibrosis to reduce the viscosity of the sticky secretions in the lungs. Administered by… …   The new mediacal dictionary

  • DNAse — Abbreviation for deoxyribonuclease Any enzyme that catalyses the cleavage of DNA phosphodiester bonds. DNAse I is a digestive endonuclease secreted by the pancreas, that degrades DNA into shorter fragments. Many other endonucleases and… …   Glossary of Biotechnology

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