Nonsense codon
A set of three adjacent bases in the DNA or their complementary bases in messenger RNA that specifies the premature end of a polypeptide chain. The three nonsense codons in messenger RNA are UAA, UAG, and UGA. When these codons are in their normal locations at the end of a sequence coding for a normal polypeptide, they are called termination or stop codons. U = uracil; A = adenine; G = guanine.

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termination c.

Medical dictionary. 2011.

Look at other dictionaries:

  • nonsense codon — (= nonsense triplet) The three codons, UAA (known as ochre), UAG (amber) and UGA (opal), that do not code for an amino acid but act as signals for the termination of protein synthesis. Any mutation that causes a base change which produces a… …   Dictionary of molecular biology

  • nonsense codon — nonsense codon. См. бессмысленный кодон. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Nonsense-Codon — Als Stopcodon, auch Nonsense Codon wird in der Genetik ein Basentriplett (Codon) der Desoxyribonukleinsäure (DNA) beziehungsweise der Ribonukleinsäure (RNA) bezeichnet, für das keine zugehörige tRNA (Transfer RNA) vorliegt und somit den Abbruch… …   Deutsch Wikipedia

  • nonsense codon — beprasmiškasis kodonas statusas T sritis augalininkystė apibrėžtis Kodonas, kuris nekoduoja jokios aminorūgšties. atitikmenys: angl. nonsense codon rus. бессмысленный кодон …   Žemės ūkio augalų selekcijos ir sėklininkystės terminų žodynas

  • nonsense codon — A codon that does not code for an amino acid but is a signal to terminate protein synthesis …   Dictionary of microbiology

  • nonsense codon — see nonsense mutation …   Dictionary of invertebrate zoology

  • Nonsense mediated decay — (NMD) is a cellular mechanism of mRNA surveillance to detect nonsense mutations and prevent the expression of truncated or erroneous proteins. In mammals, NMD is triggered by exon junction complexes (EJC), which are initially deposited during pre …   Wikipedia

  • Nonsense-mediated decay — (NMD) is a cellular mechanism of mRNA surveillance that functions to detect nonsense mutations and prevent the expression of truncated or erroneous proteins. Following transcription, precursor mRNA undergoes an assemblage of ribonucleoprotein… …   Wikipedia

  • Nonsense mutation — In genetics, a nonsense mutation is a point mutation in a sequence of DNA that results in a premature stop codon, or a nonsense codon in the transcribed mRNA, and in a truncated, incomplete, and usually nonfunctional protein product. It differs… …   Wikipedia

  • Nonsense mutation — A mutation (a change) in a base in the DNA that prematurely stops the translation (reading) of messenger RNA (mRNA) resulting in a polypeptide chain that ends prematurely and a protein product that is truncated (abbreviated) and incomplete and… …   Medical dictionary

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