nvCJD
New variant Creutzfeldt-Jakob disease, a human disease thought due to the same infectious agent as bovine spongiform encephalopathy (BSE), or mad cow disease. Both the human and bovine disorders are invariably fatal brain diseases with unusually long incubation periods measured in years, and are caused by an unconventional transmissible agent, a prion, resulting in the deposition of amyloid tissue that causes a breakdown of brain tissue leaving the infected brain with a "spongy" ("spongiform") appearance. The disease in humans is sometimes called variant Creutzfeldt-Jakob disease (vCJD). The BSE agent has been identified in the brain, spinal cord, retina, dorsal root ganglia (nervous tissue located near the backbone), and the bone marrow of cattle experimentally infected with this agent by the oral route. In addition to cattle, sheep are susceptible to experimental infection with the BSE agent by the oral route. Thus, in countries where flocks of sheep and goats may have been exposed to the BSE agent through contaminated feed, there exists a theoretical risk that these animals may have developed infections caused by the BSE agent and that these infections have been maintained in the flocks, even in the absence of continued exposure to contaminated feed (for example, through maternal transmission). Everyone with nvCJD appear to have eaten beef and beef products at some time during their lives (but then so have most of the population). Investigation of a cluster of cases with nvCJD disclosed that most of the people were likely infected through their diet. Beef carcass meat appears to have been contaminated with the BSE agent in butchers' shops where cattle heads were split.
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new variant Creutzfeldt-Jakob disease

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nvCJD abbr new variant Creutzfeldt-Jakob disease

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new variant Creutzfeldt-Jakob disease.

Medical dictionary. 2011.

Look at other dictionaries:

  • nvCJD — (new variant Creutzfeld Jacob Disease) CJD with shorter incubation …   English contemporary dictionary

  • nvCJD — abbreviation new variant Creutzfeldt–Jakob disease …   English new terms dictionary

  • nvCJD — • new variant Creutzfeldt Jakob disease …   Dictionary of medical acronyms & abbreviations

  • nvCJD — abbrev New variant Creutzfeldt Jakob disease * * * abbr. see vCJD …   Useful english dictionary

  • Creutzfeldt-Jakob disease new variant — (nvCJD) a variant of Creutzfeldt Jakob disease occurring almost exclusively in the United Kingdom, having a younger age of onset than is seen in Creutzfeldt Jakob disease, and caused by the same agent that causes bovine spongiform encephalopathy …   Medical dictionary

  • Прионы — МКБ 10 A81 МКБ 9 046046 У этого термина существуют и другие значения, см. Прионы (значения). Не путать с гипотетическими элементарными частицами  преонами Прионы (от англ. p …   Википедия

  • Прион — Белок, образующий β амилоиды предшественник прионов Не путать с гипотетическими элементарными частицами  преонами Прионы (от англ. proteinaceous infectious particles  белковые заразные частицы)  особый класс инфекционных агентов, чисто белковых,… …   Википедия

  • Прионная болезнь — Белок, образующий β амилоиды предшественник прионов Не путать с гипотетическими элементарными частицами  преонами Прионы (от англ. proteinaceous infectious particles  белковые заразные частицы)  особый класс инфекционных агентов, чисто белковых,… …   Википедия

  • Прионная инфекция — Белок, образующий β амилоиды предшественник прионов Не путать с гипотетическими элементарными частицами  преонами Прионы (от англ. proteinaceous infectious particles  белковые заразные частицы)  особый класс инфекционных агентов, чисто белковых,… …   Википедия

  • New variant Creutzfeldt-Jakob disease — Abbreviated nvCJD. A human disease thought due to the same infectious agent as bovine spongiform encephalopathy (BSE), or mad cow disease. Both the human and bovine disorders are invariably fatal brain diseases with unusually long incubation… …   Medical dictionary

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