Osteosarcoma
: A cancer of the bone that is most common in children. Also called osteogenic sarcoma.
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SYN: osteogenic sarcoma.
- parosteal o. low-grade o. arising on the surface of bone without involvement of the underlying marrow, usually occurring as a heavily ossified mass of the distal femur in women in the third and fourth decades of life.
- periosteal o. chondroblastic o. occurring on the surface of bones without involvement of the marrow; usually presents in adolescents and young adults as a lucent defect with bone spicules extending into soft tissues. Histologically, the tumor is intermediate to high grade, and the cartilage is lobulated.

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os·teo·sar·co·ma -sär-'kō-mə n, pl -mas also -ma·ta -mət-ə a sarcoma derived from bone or containing bone tissue called also osteogenic sarcoma

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n.
a highly malignant tumour arising from within a bone, usually in the metaphysis of the long bones of the body and especially around the knee and the proximal end of the humerus. It is usually seen in children and adolescents but can occur in adults of all ages, occasionally in association with Paget's disease of bone. In children the usual site for the tumour is the leg, particularly the femur. Secondary growths (metastases) are common, most frequently in the lungs (though other sites, such as the liver, may also be involved). The symptoms are usually pain and swelling at the site of the tumour and there is often a history of preceding trauma, although it is doubtful whether this contributes to the cause. Treatment of disease localized to the primary site was traditionally by amputation of the limb; limb-sparing surgery is now possible after neoadjuvant chemotherapy, with replacement of the diseased bone by a metal prosthesis. Many centres also give adjuvant therapy in an attempt to kill any microscopic tumour that might have already spread. The drugs used include doxorubicin, cisplatin, vincristine, cyclophosphamide, and methotrexate.

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os·teo·sar·co·ma (os″te-o-sahr-koґmə) [osteo- + sarcoma] a malignant primary neoplasm of bone composed of a malignant connective tissue stroma with evidence of malignant osteoid, bone, or cartilage formation. Classical osteosarcoma is a poorly differentiated tumor affecting mainly young adults, most often involving the long bones, and is classified as osteoblastic, chondroblastic, or fibroblastic according to which histologic component predominates. Called also osteogenic sarcoma. osteosarcomatous adj

Medical dictionary. 2011.

Look at other dictionaries:

  • Osteosarcoma — Classification and external resources Intermediate magnification micrograph of an osteosarcoma (center and right of image) adjacent to non malignant bone (left bottom of image). The top right of the image has poorly differentiated tumor. Osteoid… …   Wikipedia

  • osteosarcoma — m. oncol. Tumor maligno óseo formado por tejido conjuntivo maligno que produce metástasis pulmonar rápidamente. Suele producirse en la tibia y/o en el fémur de niños y adolescentes varones. El tratamiento se realiza con radioterapia,… …   Diccionario médico

  • Osteosarcoma — Os te*o*sar*co ma, n.; pl. {Osteosarcomata}. [NL. See {Osteo }, and {sarcoma}.] (Med.) A tumor having the structure of a sarcoma in which there is a deposit of bone; sarcoma connected with bone. [1913 Webster] …   The Collaborative International Dictionary of English

  • osteosarcoma — (de «osteo » y «sarcoma») m. Med. Sarcoma de los huesos …   Enciclopedia Universal

  • osteosarcoma — sustantivo masculino 1. Área: medicina Tumor maligno formado por tejido óseo …   Diccionario Salamanca de la Lengua Española

  • osteosarcoma — [äs΄tē ō sär kō′mə] n. pl. osteosarcomas, osteosarcomata [äs΄tē ō sär kō′mə tə] a common type of sarcoma of the bone characterized by rapid spreading, esp. to the lungs, and pain, swelling, etc. in the large, long bones …   English World dictionary

  • Osteosarcoma — En este artículo se detectó el siguiente problema: Requiere una revisión ortográfica y gramatical. Por favor, edítalo para mejorarlo, o debate en la discusión …   Wikipedia Español

  • osteosarcoma — /os tee oh sahr koh meuh/, n., pl. osteosarcomas, osteosarcomata / meuh teuh/. Pathol. a malignant tumor of the bone. [1800 10; OSTEO + SARCOMA] * * * ▪ medicine also called  osteogenic sarcoma        most common bone cancer, primarily affecting… …   Universalium

  • osteosarcoma — {{#}}{{LM O28444}}{{〓}} {{[}}osteosarcoma{{]}} ‹os·te·o·sar·co·ma› {{《}}▍ s.m.{{》}} Tumor maligno del tejido óseo. {{★}}{{\}}ETIMOLOGÍA:{{/}} Del griego ostéon (hueso) y sarcoma …   Diccionario de uso del español actual con sinónimos y antónimos

  • osteosarcoma — noun (plural mas; also osteosarcomata) Etymology: New Latin Date: circa 1826 a sarcoma derived from bone or containing bone tissue …   New Collegiate Dictionary

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