Psoriasis
: A reddish, scaly rash often located over the surfaces of the elbows, knees, scalp, and around or in the ears, navel, genitals or buttocks. Approximately 10-15% of patients with psoriasis develop joint inflammation (inflammatory arthritis). It is caused by the body making too many skin cells, and in some cases it is believed to be an autoimmune condition. Treatment options include topical steroid creams, tar soap preparations, and exposure to ultraviolet light. See also psoriasis, guttate;
* * *
A common multifactorial inherited condition characterized by the eruption of circumscribed, discrete and confluent, reddish, silvery-scaled maculopapules; the lesions occur predominantly on the elbows, knees, scalp, and trunk, and microscopically show characteristic parakeratosis and elongation of rete ridges with shortening of epidermal keratinocyte transit time due to decreased cyclic guanosine monophosphate. [G. p., fr. psora, the itch]
- p. annularis, p. annulata SYN: p. circinata.
- p. arthropica p. associated with severe arthritis resembling rheumatoid arthritis, although serum rheumatoid factor is absent.
- p. circinata p. in which healing is taking place at the center of the lesion while the process continues at the periphery, producing a ring-shaped or annular lesion. SYN: p. annularis, p. annulata.
- p. diffusa, diffused p. a form of p. with extensive coalescence of the lesions.
- exfoliative p. exfoliative dermatitis developing from chronic p., sometimes resulting from overtreatment of p..
- flexural p. p. involving intertriginous folds, e.g., axillary and inguinal skin, which may resemble seborrheic dermatitis.
- generalized pustular p. of Zambusch SYN: pustular p. (1).
- p. geographica p. gyrata in which the lesions suggest the coast outline on a map.
- p. guttata p. occurring abruptly in round patches of small size; seen in young persons following streptococcal infections.
- p. gyrata p. circinata in which there is a coalescence of the rings giving rise to figures of various outlines.
- p. nummularis p. in which the lesions are discrete and discoid.
- palmar p. patchy, hyperkeratotic p. affecting contact points of the volar surface of fingers and palms, alone or with mild p. elsewhere; believed to be an isomorphic response, it may affect one palm involved in a sport or occupation.
- p. punctata p. in which the individual lesions are papules, each red in color and tipped with a single white scale.
- pustular p. 1. an extensive exacerbation of p., with pustule formation in the normal and psoriatic skin, fever, and granulocytosis; sometimes precipitated by oral steroids; SYN: generalized pustular p. of Zambusch. 2. a local pustular eruption of the palms and soles, occurring most commonly in a patient with p.; difficult to distinguish from acrodermatitis continua.

* * *

pso·ri·a·sis sə-'rī-ə-səs n, pl -a·ses -.sēz a chronic skin disease characterized by circumscribed red patches covered with white scales

* * *

n.
a chronic skin disease in which scaly pink patches form on the elbows, knees, scalp, and other parts of the body. Psoriasis is one of the commonest skin diseases in Britain, affecting about 2% of the population, but its cause is not known. The disorder often runs in families, the commonest time of onset being in adolescence. It sometimes occurs in association with arthritis (see psoriatic arthritis). Occasionally the disease may be very severe, affecting much of the skin and causing considerable disability in the patient. While psychological stress may cause an exacerbation of psoriasis, the only significant event that precipitates the disease is a preceding streptococcal infection. Drugs, such as lithium or beta blockers, may occasionally be responsible.
Although there is as yet no cure, treatment of psoriasis has improved greatly in recent years. Tar and dithranol may still be used and topical corticosteroids remain popular. The vitamin D analogues, e.g. calcipotriol, are highly effective, while PUVA is an effective treatment for moderately severe disease. Systemic therapy, such as methotrexate, retinoid, or ciclosporin, is reserved for the worst cases.

* * *

pso·ri·a·sis (sə-riґə-sis) [Gr. psōriasis] any of a group of common chronic, squamous dermatoses with variable symptoms and courses; some are inherited. Principal histological findings are Munro microabscesses and spongiform pustules; also seen are rounded, circumscribed, erythematous, dry, scaling patches of various sizes, covered by gray, silvery, or white, umbilicated, lamellar scales. The most common sites are extensor surfaces, nails, scalp, genitalia, and the lumbosacral region. psoriatic adj

Psoriasis.


Medical dictionary. 2011.

Look at other dictionaries:

  • Psoriasis — Classification and external resources A person whose back and arms are affected by psoriasis ICD 10 L …   Wikipedia

  • psoriasis — [ psɔrjazis ] n. m. • 1822; gr. méd. psôriasis, de psôra « gale » ♦ Méd. Maladie de la peau de cause inconnue, à évolution chronique, caractérisée par des taches rouges recouvertes de squames abondantes, blanchâtres, sèches et friables,… …   Encyclopédie Universelle

  • psoriasis — f. dermat. Enfermedad de la piel que se caracteriza por la aparición de lesiones eritematosas y escamosas acompañadas de picor; cuando se rascan aparece una superficie roja brillante. Con el tiempo, estas lesiones tienden a confluir formando… …   Diccionario médico

  • psoriasis — 1684, from L.L. psoriasis mange, scurvy, from Gk. psoriasis being itchy, from psorian to have the itch, from psora itch, related to psen to rub …   Etymology dictionary

  • psoriasis — (plural psoriasis) sustantivo femenino 1. Soriasis. soriasis o psoriasis (plural soriasis) sustantivo femenino 1. ( …   Diccionario Salamanca de la Lengua Española

  • psoriasis — ‘Dermatosis generalmente crónica’. Es femenino, al igual que el resto de las voces médicas que presentan la terminación griega (ia)sis: candidiasis, litiasis, midriasis, etc. No es correcto su uso en masculino: ⊕ el psoriasis. También es válida,… …   Diccionario panhispánico de dudas

  • psoriasis — [sə rī′ə sis] n. [ModL < Gr psōriasis < psōra, an itch, akin to psēn, to rub, scratch, psammos, SAND] a chronic skin disease characterized by scaly, reddish patches psoriatic [sō΄rē at′ik] adj …   English World dictionary

  • Psoriasis — Pso*ri a*sis, n. [NL., fr. Gr. ?, fr. ? psora.] (Med.) (a) The state of being affected with psora. [Obs.] (b) A cutaneous disease, characterized by imbricated silvery scales, affecting only the superficial layers of the skin. [1913 Webster] …   The Collaborative International Dictionary of English

  • psoriasis — psoriasis. См. псориаз. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Psoriăsis — (Schuppengrind, Schuppenflechte, Räude), chronischer Hautausschlag in größeren od. kleineren verschiedenartig gestalteten u. ein wenig erhabenen Flecken von rother od. rothbrauner, dem Fingerdruck nur unvollständig weichender Farbe bestehend, auf …   Pierer's Universal-Lexikon

  • Psoriăsis — (griech.), s. Schuppenflechte. P. buccalis, s. Leukoplakie …   Meyers Großes Konversations-Lexikon

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”