Pyridoxine
One of the vitamin B6 group (which also includes pyridoxal and pyridoxamine) that is transformed in the body to pyridoxal phosphate, which functions as a coenzyme, a substance that enhances the action of an enzyme and thereby helps catalyze and speed a biochemical reaction. (A number of vitamins serve as coenzymes.) The vitamin B6 group is especially important to the function of the central nervous system, skin, and blood. Vitamin B6 is involved in the formation of red blood cells since pyridoxal phosphate is the rate-limiting substance in making heme, a component of hemoglobin, the key oxygen-carrying pigment in red blood cells. The diet rarely lacks vitamin B6. Most foods contain it. However, deficiency of vitamin B6 within the body may occur due to poor absorption of it from the intestine or inactivation of it by some drugs (e.g., anticonvulsants, corticosteroids, estrogens, isoniazid, and penicillamine). Other causes of vitamin B6 include alcoholism and conditions such as hyperthyroidism and diabetes that increase the metabolic demand, creating a relative shortage of vitamin B6. Vitamin B6 deficiency causes convulsions in infants and anemia in adults. An outbreak of convulsions in infants followed the inadvertent destruction of vitamin B6 in infant formulas. Several genetic syndromes also involve problems with vitamin B6.
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The original vitamin B6, which term now includes pyridoxal and pyridoxamine, associated with the utilization of unsaturated fatty acid s. In rats, deficiency produces a nutritional dermatitis and acrodynia; in humans, deficiency may result in increased irritability, convulsions, and peripheral neuritis. The hydrochloride is used in pharmaceutic preparations; found in vegetables.

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pyr·i·dox·ine .pir-ə-'däk-.sēn, -sən n a crystalline phenolic alcohol C8H11NO3 of the vitamin B6 group found esp. in cereals and convertible in the body into pyridoxal and pyridoxamine

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n.

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pyr·i·dox·ine (pēr″ĭ-dokґsēn) one of the forms of vitamin B6> (q.v.).

Medical dictionary. 2011.

Look at other dictionaries:

  • Pyridoxine — Pyridoxine[1] IUPAC name …   Wikipedia

  • pyridoxine — [ piridɔksin ] n. f. • 1942; en angl. 1939; de pyridine ♦ Méd. Vitamine B6 extraite de levures, de graines de céréales, de tissus animaux, prescrite dans certaines affections de la peau et des nerfs (polynévrites). ● pyridoxine nom féminin La… …   Encyclopédie Universelle

  • Pyridoxine — Général Nom IUPAC 4,5 bis(hydroxyméthyl) 2 méthylpyridin 3 ol No CAS …   Wikipédia en Français

  • pyridoxine — pyridoxine. См. пиридоксин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • pyridoxine — [pir΄ə däk′sēn΄, pir΄ə däk′sin] n. [ PYRID(INE) + OX(Y) + INE3] a complex pyridine, C8H11NO3, one of the vitamins of the B6 group, found in various foods and prepared synthetically, usually as the hydrochloride: known to prevent nutritional… …   English World dictionary

  • pyridoxine — piridoksolis statusas T sritis chemija formulė HOC₅HN(CH₃)(CH₂OH)₂ atitikmenys: angl. pyridoxine; pyridoxol; vitamin B₆ rus. витамин В₆; пиридоксин; пиридоксол ryšiai: sinonimas – piridoksinas sinonimas – 4,5 di(hidroksimetil) 2 metil 3… …   Chemijos terminų aiškinamasis žodynas

  • pyridoxine — A key nutrient that the body needs to break down proteins, carbohydrates, and fats in food for healthy blood, skin, and nerves. It is found in many foods, including meats, bananas, legumes, eggs, and whole grains. Pyridoxine is being studied in… …   English dictionary of cancer terms

  • pyridoxine — noun Etymology: pyridine + ox + 2 ine Date: 1939 a crystalline phenolic alcohol C8H11NO3 of the vitamin B6 group found especially in cereals and convertible in the organism into pyridoxal and pyridoxamine …   New Collegiate Dictionary

  • pyridoxine — /pir i dok seen, sin/, n. Biochem. a derivative of pyridine, C8H11NO3, occurring in whole grain cereals, meats, fish, etc., and also made synthetically: required for the prevention of pellagra and the formation of hemoglobin; vitamin B6. Also,… …   Universalium

  • pyridoxine — noun A derivative of pyridine found in fish, liver, cereals and yeast that is essential for the metabolism of amino acids and starch. Syn: vitamin B<sub>6</sub> …   Wiktionary

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