Reading frame
One of the three possible ways to read a nucleotide sequence in DNA (depending upon whether reading starts with the first, second or third base in a triplet).
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The grouping of nucleotides by threes into codons. See frame-shift mutation.
- blocked r. a sequence of DNA that cannot be translated into a viable protein; usually due to the interruption by one or more termination codons. SYN: closed r..
- closed r. SYN: blocked r..
- open r. a gene presumed to code for a protein but for which no gene product has been identified; also known as unidentified r.. SYN: unidentified r..
- unidentified r. (URF) SYN: open r..

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read·ing frame 'rēd-iŋ- n any of the three possible ways of reading a sequence of nucleotides as a series of triplets see OPEN READING FRAME

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one of the three possible ways of reading a nucleotide sequence as a series of triplets. An open reading frame contains no termination codons and is thus potentially translatable into protein.

Medical dictionary. 2011.

Look at other dictionaries:

  • Reading frame — In biology, a reading frame is a contiguous and non overlapping set of three nucleotide codons in DNA or RNA. There are 3 possible reading frames in a mRNA strand and six in a double stranded DNA molecule due to the two strands from which… …   Wikipedia

  • reading frame — The reading frame defines which sets of three nucleotides are read as triplets, and hence as codons, in DNA transcription. The start point is usually determined by the initiation codon, AUG. Thus the sequence AUGGCAAAA would be read as… …   Glossary of Biotechnology

  • reading frame — noun : any of the three possible ways of reading a sequence of nucleotides as a series of triplets see open reading frame herein …   Useful english dictionary

  • reading frame — skaitymo rėmelis statusas T sritis augalininkystė apibrėžtis Vienas iš trijų galimų nukleotidų sekos skaitymo būdų. atitikmenys: angl. reading frame rus. рамка считывания …   Žemės ūkio augalų selekcijos ir sėklininkystės terminų žodynas

  • reading frame — One of the three possible ways of reading a nucleotide sequence. As the genetic code is read in non overlapping triplets (codons) there are three possible ways of translation of a sequence of nucleotides into a protein, each with a different… …   Dictionary of molecular biology

  • reading frame — The way in which nucleotides in DNA and mRNA are grouped into codons or groups of three for reading the message contained in the nucleotide sequence …   Dictionary of microbiology

  • reading frame — noun Date: 1965 a sequence of nucleotide triplets that is potentially translatable into a polypeptide and that is determined by the placement of a codon that initiates translation …   New Collegiate Dictionary

  • reading frame —    The DNA codon sequence transcribed into pre mRNA …   Forensic science glossary

  • reading frame mutation — reading frame mutation. См. мутация со сдвигом фазы. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • reading frame mutations — reading frame mutations. = frameshift mutations (см.). (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

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