Recombination
The trading of fragments of genetic material between chromosomes before the egg and sperm cells are created. Key features of recombination include the point-to-point association of paired chromosomes (synapsis) followed by the visible exchange of segments (crossing over) at X-shaped crosspoints (chiasmata). Recombination is the principal way of creating genetic diversity between generations. By shuffling the genetic deck of cards, recombination ensures that children are dealt a different genetic hand than their parents.
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1. The process of reuniting of parts that had become separated. 2. The reversal of coupling phase in meiosis as gauged by the resulting phenotype. SEE ALSO: recombinant. 3. The formation of new combinations of genes.
- genetic r. 1. the presence in progeny of combinations of genotypes and perhaps phenotypes, not present in either parent, resulting from crossing-over; 2. in microbial genetics, the inclusion of a chromosomal part or extrachromosomal element of one microbial strain in the chromosome of another; the interchange of chromosomal parts or genes between different microbial strains.
- homologous r. the exchange of corresponding stretches of DNA between two sister chromosomes.
- site-specific r. integration of foreign DNA into a particular site in the host genome.

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re·com·bi·na·tion .rē-.käm-bə-'nā-shən n the formation by the processes of crossing-over and independent assortment of new combinations of genes in progeny that did not occur in the parents
re·com·bi·na·tion·al -shnəl, -shən-əl adj

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re·com·bi·na·tion (re″kom-bĭ-naґshən) 1. the reunion, in the same or a different arrangement, of formerly united elements which have become separated. 2. in genetics, the process that creates new combinations of genes by shuffling the linear order of the DNA, such as occurs naturally by crossing over of homologous chromosomes during meiosis or of homologous DNA sequences in somatic cells during mitosis, or occurs in vitro when DNA or RNA is manipulated for genetic engineering.

Medical dictionary. 2011.

Look at other dictionaries:

  • Recombination — may refer to: * Genetic recombination, the process by which genetic material is broken and joined to other genetic material * Carrier generation and recombination, processes by which mobile electrons and electron holes are created and eliminated… …   Wikipedia

  • Recombination — Re*com bi*na tion (r?*k?m b?*n? sh?n), n. Combination a second or additional time. [1913 Webster] …   The Collaborative International Dictionary of English

  • recombination — recombination. См. рекомбинация. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • recombination — 1791, from RE (Cf. re ) + COMBINATION (Cf. combination) …   Etymology dictionary

  • recombination — [rē käm΄bə nā′shən] n. 1. a combining again 2. Genetics the appearance in offspring of new combinations of allelic genes not present in either parent, produced from the mixing of genetic material, as by crossing over …   English World dictionary

  • recombination — /ree kom beuh nay sheuhn/, Genetics. the formation of new combinations of genes, either naturally, by crossing over or independent assortment, or in the laboratory by direct manipulation of genetic material. [1820 30, for general sense; 1900 05… …   Universalium

  • recombination — The creation, by a process of intermolecular exchange, of chromosomes combining genetic information from different sources, typically two genomes of a given species. Site specific, homologous, transpositional and non homologous (illegitimate)… …   Dictionary of molecular biology

  • recombination — rekombinacija statusas T sritis automatika atitikmenys: angl. recombination vok. Rekombination, f rus. рекомбинация, f pranc. recombinaison, f …   Automatikos terminų žodynas

  • recombination — rekombinacija statusas T sritis chemija apibrėžtis Krūvininkų poros išnykimas. atitikmenys: angl. recombination rus. рекомбинация …   Chemijos terminų aiškinamasis žodynas

  • recombination — rekombinacija statusas T sritis chemija apibrėžtis Laisvųjų radikalų susijungimas. atitikmenys: angl. recombination rus. рекомбинация …   Chemijos terminų aiškinamasis žodynas

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