Relaxin

Relaxin
A hormone produced during pregnancy that facilitates the birth process by causing a softening and lengthening of the cervix and the pubic symphysis (the place where the pubic bones come together). Relaxin also inhibits contractions of the uterus and may play a role in timing of delivery. Relaxin works by simultaneously cutting collagen production and increasing collagen breakdown. A synthetic form of relaxin has been reported to be useful in treating scleroderma (a connective tissue disease that causes the skin to become tight and thick), improving the skin condition, mobility, and function.
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A polypeptide hormone secreted by the corpora lutea of mammalian species during pregnancy. Facilitates the birth process by causing a softening and lengthening of the pubic symphysis and cervix; it also inhibits contraction of the uterus and may play a role in timing of parturition. SYN: cervilaxin, ovarian hormone, releasin. [relax + -in]

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re·lax·in ri-'lak-sən n a polypeptide sex hormone of the corpus luteum that facilitates birth by causing relaxation of the pelvic ligaments

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n.
a hormone, secreted by the placenta in the terminal stages of pregnancy, that causes the cervix (neck) of the uterus to dilate and prepares the uterus for the action of oxytocin during labour.

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re·lax·in (re-lakґsin) a water-soluble polypeptide (molecular weight approx. 8000) extractable from the corpus luteum of pregnancy; it produces relaxation of the pubic symphysis and dilation of the uterine cervix in certain animal species. Its role in the pregnant human female is uncertain.

Medical dictionary. 2011.

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  • relaxin — relaxin. См. релаксин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Relaxin — Relaxin, gegen Ende der Schwangerschaft von Uterus und Placenta gebildetes ⇒ Sexualhormon, das vor der Geburt die Symphyse des mütterlichen Beckens erweitert …   Deutsch wörterbuch der biologie

  • relaxin — ☆ relaxin [ri lak′sin ] n. [ RELAX + IN1] a polypeptide hormone associated with pregnancy, used experimentally to relax the pelvic ligaments, as in childbirth …   English World dictionary

  • Relaxin — For the Miles Davis album, see Relaxin with the Miles Davis Quintet . protein Name = Relaxin 1 caption = width = HGNCid = 10026 Symbol = RLN1 AltSymbols = EntrezGene = 6013 OMIM = 179730 RefSeq = UniProt = PDB = ECnumber = Chromosome = 9 Arm = q… …   Wikipedia

  • Relaxin — Relaxine sind Peptidhormone in Wirbeltieren, die erstmals 1926 von Frederick Lee Hisaw beschrieben wurden. Im Menschen sind drei Relaxine bekannt, ebenso wie vier Relaxin Rezeptoren, wobei sowohl Relaxin 1 und 2 an die Relaxin Rezeptoren 1 und 2… …   Deutsch Wikipedia

  • relaxin — Polypeptide hormone produced by corpus luteum and found in the blood of pregnant animals. Acts, as its name suggests, to cause muscle relaxation during parturition. Human relaxin has an A chain of 24 amino acids and a B chain of 29. Has… …   Dictionary of molecular biology

  • Relaxin — Re|la|xin [lat. relaxare = erweitern, lockern, nachlassen, erholen; ↑ in (3)], das; s, e; Abk.: RLX: den weiblichen Sexualhormonen zugerechnetes, aus zwei Peptidketten mit 24 bzw. 32 Aminosäureresten bestehendes Peptid Hormon (MG 6333), das für… …   Universal-Lexikon

  • Relaxin/insulin-like family peptide receptor 1 — Relaxin/insulin like family peptide receptor 1, also known as RXFP1, is a human gene.cite web | title = Entrez Gene: RXFP1 relaxin/insulin like family peptide receptor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Relaxin/insulin-like family peptide receptor 2 — Relaxin/insulin like family peptide receptor 2, also known as RXFP2, is a human gene.cite web | title = Entrez Gene: RXFP2 relaxin/insulin like family peptide receptor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Relaxin/insulin-like family peptide receptor 3 — Relaxin/insulin like family peptide receptor 3, also known as RXFP3, is a human gene.cite web | title = Entrez Gene: RXFP3 relaxin/insulin like family peptide receptor 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

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