Sentinel lymph node
The first lymph node ("gland") to receive lymphatic drainage from a tumor. Which lymph node is the sentinel node in a given case is determined by injecting around the tumor a tracer substance that will travel through the lymphatic system to the first draining (sentinel) node and identify it. The tracer substance may be blue dye that can be visually tracked or a radioactive colloid hat can be radiologically followed. Biopsy of the sentinel lymph node can reveal whether there are lymphatic metastases. If the sentinel node contains tumor cells, removal of more nodes in the area may be warranted. If the sentinel node is normal, this obviates the need for extensive dissection of the regional lymph-node basin. Sentinel-lymph-node biopsy has, for example, become a standard technique for determining the nodal stage of disease in patients with malignant melanoma.

Medical dictionary. 2011.

Look at other dictionaries:

  • Sentinel lymph node — The sentinel lymph node is the hypothetical first lymph node or group of nodes reached by metastasizing cancer cells from a tumor.PhysiologyThe spread of some forms of cancer usually follows an orderly progression, spreading first to regional… …   Wikipedia

  • sentinel lymph node — the first lymph node to show evidence of metastasis of a malignant tumour (e.g. breast cancer) via the lymphatic system. Absence of cancer cells in the sentinel node indicates that more distal lymph nodes will also be free of metastasis …   Medical dictionary

  • sentinel lymph node — the first lymph node to show evidence of metastasis of a malignant tumour (e.g. breast cancer) via the lymphatic system. Absence of cancer cells in the sentinel node indicates that more distal lymph nodes will also be free of metastasis …   The new mediacal dictionary

  • sentinel lymph node — The first lymph node to which cancer is likely to spread from the primary tumor. When cancer spreads, the cancer cells may appear first in the sentinel node before spreading to other lymph nodes …   English dictionary of cancer terms

  • Sentinel-lymph-node biopsy — Examination of the first lymph node ( gland ) that receives lymphatic drainage from a tumor to learn whether that node does or does not have tumor cells within it. Which lymph node is the sentinel node for a given tumor is determined by injecting …   Medical dictionary

  • sentinel lymph node biopsy — Removal and examination of the sentinel node(s) (the first lymph node(s) to which cancer cells are likely to spread from a primary tumor). To identify the sentinel lymph node(s), the surgeon injects a radioactive substance, blue dye, or both near …   English dictionary of cancer terms

  • sentinel lymph node mapping — The use of dyes and radioactive substances to identify the first lymph node to which cancer is likely to spread from the primary tumor. Cancer cells may appear first in the sentinel node before spreading to other lymph nodes and other places in… …   English dictionary of cancer terms

  • Biopsy, sentinel-lymph-node — Examination of the first lymph node ( gland ) that receives lymphatic drainage from a tumor to learn whether that node does or does not have tumor cells within it. Which lymph node is the sentinel node for a given tumor is determined by injecting …   Medical dictionary

  • Lymph node, sentinel — The first lymph node ( gland ) to receive lymphatic drainage from a tumor. Which lymph node is the sentinel node for a given tumor is determined by injecting around the tumor a tracer substance that will travel through the lymphatic system to the …   Medical dictionary

  • Node, sentinel lymph — The first lymph node ( gland ) to receive lymphatic drainage from a tumor. Which lymph node is the sentinel node for a given tumor is determined by injecting around the tumor a tracer substance that will travel through the lymphatic system to the …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”