Association (genetics)
In genetics, the word "association" has a very specific and special meaning. It refers to the occurrence together of two or more characteristics more often than would be expected by chance alone. Association is to be distinguished from linkage: the tendency for certain genes to be inherited together because they are on the same chromosome. Let us take linkage first. The genes for red-green colorblindness, hemophilia and Duchenne muscular dystrophy might be found to be linked, since all three genes are on the same chromosome, the X chromosome, and they are passed along as a package to a child. An example of association involves blood types and duodenal ulcer. A person with blood type O has almost a 60% greater risk of a duodenal ulcer than someone with blood type AB (which is coded at the same chromosome location as blood group O). Blood group O and duodenal ulcer are said to be associated. An even stronger association involves a feature on the surface of white blood cells, the HLA type (HLA stands for human leukocyte antigen). A particular HLA type, HLA type B-27, is associated with an increased risk for a number of diseases including ankylosing spondylitis. The extent of the association is enormous. The disease is 87 times more likely in bearers of HLA B-27 than in the rest of the population.

Medical dictionary. 2011.

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  • association — association. См. ассоциация [хромосом]. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • association — association. См. синапсис. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Genetics — This article is about the general scientific term. For the scientific journal, see Genetics (journal). Part of a series on Genetics Key components Chromosome DNA • RNA Genome …   Wikipedia

  • Genetics Society of America — The Genetics Society of America is a non exclusive association of genetics researchers and educators, and the publisher of the peer reviewed journal Genetics .The Genetics Society of America was established in 1931. It includes over 4000… …   Wikipedia

  • association — 1. A connection of persons, things, or ideas by some common factor. 2. A functional connection of two ideas, events, or psychologic phenomena established through learning or experience. SEE ALSO: conditioning. 3. Statistical dependence between… …   Medical dictionary

  • Association du personnel de la Confédération — L Association du personnel de la Confédération APC est un syndicat suisse. Sommaire 1 Membres 2 Sections 3 Voir aussi 3.1 Liens internes …   Wikipédia en Français

  • association — 1. alliance, league, coalition, union, guild, consortium, syndication, conspiracy, cabal; company, partnership, joint concern, corporation, amalgamation, combine, merger, monopoly, trust, alignment, bloc, cartel; society, organization, party,… …   A Note on the Style of the synonym finder

  • chromosome association — chromosome association. = association (см.). (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • chromosome association — chromosome association. См. ассоциация [хромосом]. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • end-to-end association — end to end association. См. ассоциация конец в конец. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

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