Atrial septal defect (ASD)
A hole in the septum, the wall, between the atria, the upper chambers of the heart. Commonly called an ASD. ASDs constitute a major class of heart formation abnormalities present at birth (congenital cardiac malformations). Normally, when clots in veins break off, they travel first to the right side of the heart and, then to the lungs where they lodge as an obstruction (embolus). The lungs act as a filter to prevent the clots from entering the arterial circulation. However, when there is an ASD, a clot can cross from the right to the left side of the heart, then pass into the arteries as a paradoxical embolism. Once in the arterial circulation, a clot can travel to the brain, block a vessel there, and cause a stroke (cerebrovascular accident). Because of the risk of stroke from paradoxical embolism, it is usually recommended that even small ASDs be closed (repaired).

Medical dictionary. 2011.

Look at other dictionaries:

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  • atrial septal defect — ASD a congenital defect of the heart in which there is a hole in the partition (septum) separating the two atria (see septal defect). There are two kinds of ASD – ostium primum and ostium secundum. Ostium primum defects are rarer but more serious …   The new mediacal dictionary

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  • Septal defect, atrial (ASD) — A hole in the septum, the wall, between the atria, the upper chambers of the heart. Commonly called an ASD. ASDs are a major class of heart deformity that is present at birth (congenital cardiac malformation) …   Medical dictionary

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