atrial natriuretic peptide

atrial natriuretic peptide
atrial natriuretic peptide n a peptide hormone secreted by myocytes of the cardiac atria that in pharmacological doses promotes salt and water excretion and lowers blood pressure abbr. ANP

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(ANP) a hormone involved in natriuresis and the regulation of renal and cardiovascular homeostasis. It is generally 28 amino acids in length but varies somewhat; it is synthesized as a prohormone in the granules of the myocytes of the atrium and is released into the circulation in response to atrial dilatation or increased intravascular fluid volume. Besides causing natriuresis, it also causes diuresis and renal vasodilation and reduces circulating concentrations of renin, aldosterone, and vasopressin, thereby normalizing circulating blood pressure and volume. Called also atriopeptin and atrial natriuretic factor.

Medical dictionary. 2011.

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  • atrial natriuretic peptide — noun Date: 1984 a peptide hormone secreted by the cardiac atria that in pharmacological doses promotes salt and water excretion and lowers blood pressure called also atrial natriuretic factor …   New Collegiate Dictionary

  • atrial natriuretic peptide — noun or atrial natriuretic factor : a peptide hormone secreted by myocytes of the cardiac atria that in pharmacological doses promotes salt and water excretion and lowers blood pressure …   Useful english dictionary

  • atrial natriuretic peptide — ANP; see natriuretic peptide …   The new mediacal dictionary

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