Sulfonylurea

Sulfonylurea
A class of oral hypoglycemic agents (pills and capsules taken to lower the level of blood glucose) by people with type 2 diabetes. The sulfonylureas increase the secretion of insulin by the pancreas. There are two generations of sulfonylureas. The main difference between the first- and second-generation sulfonylureas is in the way they are eliminated from the body. As a consequence, second-generation sulfonylureas are usually taken less frequently each day than first-generation sulfonylureas and generally are preferred when there is poor function of the kidneys. The first-generation sulfonylureas are Dymelor (acetohexamide), Diabinese (chlorpropamide), Tolinase (tolazamide), and Orinase (tolbutamide). The second-generation sulfonylureas include Glucotrol and Glucotrol XL (glipizide), DiaBeta, Micronase, and Glynase PresTab (glyburide)and Amaryl (glimepiride).

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sul·fo·nyl·urea or chiefly Brit sul·pho·nyl·urea .səl-fə-.nil-'(y)u̇r-ē-ə n any of several hypoglycemic compounds (as glipizide and tolbutamide) related to the sulfonamides and used in the oral treatment of type 2 diabetes

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sul·fo·nyl·urea (sul″fə-nəl-u-reґə) any of a class of compounds that exert hypoglycemic activity by stimulating the islet tissue to secrete insulin; used to control hyperglycemia in patients with type 2 diabetes mellitus who cannot be treated solely by diet and exercise.

Medical dictionary. 2011.

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  • sulfonylurea — [sul΄fə nil yo͞o rē′ə] n. any of a group of oral drugs, as tolbutamide, that stimulate the pancreas to secrete more insulin, used to treat diabetes …   English World dictionary

  • Sulfonylurea — Image stack align=right image size=240 image1 c Chlorpropamide Chlorpropamide image2 c Tolazamide Tolazamide image3 c Gliclazide Gliclazide image4 c GlimepirideSulfonylurea (UK: Sulphonylurea) derivatives are a class of antidiabetic drugs that… …   Wikipedia

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  • sulfonylurea — noun Etymology: New Latin, from International Scientific Vocabulary sulfonyl + New Latin urea Date: 1956 any of several hypoglycemic compounds related to the sulfonamides and used in the oral treatment of diabetes …   New Collegiate Dictionary

  • sulfonylurea — noun Any of a class of antidiabetic drugs that act by increasing insulin release from the beta cells in the pancreas …   Wiktionary

  • sulfonylurea — n. (Medicine) any of several compounds which stimulate the pancreatic islet cells to produce insulin (used as a treatment for some forms of diabetes) …   English contemporary dictionary

  • sulfonylurea — sul·fo·nyl·urea …   English syllables

  • sulfonylurea — noun antidiabetic consisting of any of several drugs that reduce the level of glucose in the blood; used to treat diabetes mellitus • Hypernyms: ↑antidiabetic, ↑antidiabetic drug • Hyponyms: ↑tolazamide, ↑Tolinase, ↑tolbutamide, ↑Orinase * * * …   Useful english dictionary

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