Syndrome, Klinefelter
A chromosome condition in boys and men that is usually due to their having 47 chromosomes with XXY sex chromosomes, rather than having the usual 46 chromosomes with XY sex chromosomes. XXY is one of the most common chromosomal abnormalities. It occurs in 1 in 500 male births. Because it is so common, Klinefelter syndrome is considered one the SCVs (sex chromosome variations). The signs of Klinefelter syndrome include small testes, insufficient production of testosterone, and infertility. XXY males are more likely than other males to show breast enlargement, lack of facial and body hair, a rounded body type, to be overweight, and be taller than their fathers and brothers. The diagnosis can be difficult to make in early childhood. Klinefelter boys tend to have learning and/or behavioral problems more often than other boys. In 1942 Drs. Harry F Klinefelter, EC Reifenstein, Jr and their mentor Fuller Albright at the Massachusetts General Hospital in Boston published a report about 9 men who had enlarged breasts, sparse facial and body hair, small testes, and inability to produce sperm. This combination of features has come to be recognized as Klinefelter syndrome. For much more information, see Klinefelter syndrome.

Medical dictionary. 2011.

Look at other dictionaries:

  • syndrome — syndromic /sin drom ik/, adj. /sin drohm, dreuhm/, n. 1. Pathol., Psychiatry. a group of symptoms that together are characteristic of a specific disorder, disease, or the like. 2. a group of related or coincident things, events, actions, etc. 3.… …   Universalium

  • Syndrome de Klinefelter — Classification et ressources externes Les personnes atteintes d un syndrome de Klinefelter ont un chromosome X supplémentaire, leur caryotype est 47,XX …   Wikipédia en Français

  • Klinefelter's syndrome — ☆ Klinefelter s syndrome [klīn′fel΄tərz ] n. [after H. Klinefelter (1912 ), U.S. physician] a congenital disorder of males, caused by the presence of an extra X chromosome and characterized by small testicles and sterility …   English World dictionary

  • Syndrome de down — « trisomie 21 » redirige ici. Pour les autres significations, voir Trisomie 21 (groupe) …   Wikipédia en Français

  • Syndrome XYY — Syndrome 47,XYY Le syndrome 47,XYY est une anomalie chromosomique caractérisée par la présence anormale d un deuxième chromosome Y. Il s agit donc d une aneuploïdie. Cette anomalie se retrouve donc uniquement chez des personnes de sexe masculin… …   Wikipédia en Français

  • Klinefelter syndrome — Klinefelter syndrome. См. синдром Клайнфельтера. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • syndrome de Klinefelter — ● syndrome de Klinefelter Maladie héréditaire caractérisée par une anomalie du développement des tubules séminifères des testicules …   Encyclopédie Universelle

  • Klinefelter's syndrome — Infobox Disease ICD10 = ICD10|Q|98|0|q|90 ICD10|Q|98|4|q|90 ICD9 = ICD9|758.7 Caption = 47,XXY ICDO = OMIM = MedlinePlus = eMedicineSubj = ped eMedicineTopic = 1252 MeshID = D007713 Klinefelter s syndrome, 47,XXY or XXY syndrome is a condition… …   Wikipedia

  • Klinefelter-Reifenstein-Albricht-Syndrom — Klassifikation nach ICD 10 Q98.0 Klinefelter Syndrom, Karyotyp 47,XXY …   Deutsch Wikipedia

  • Klinefelter syndrome — A chromosome condition in boys and men that is usually due to their having 47 chromosomes with XXY sex chromosomes, rather than having the usual 46 chromosomes with XY sex chromosomes. XXY is one of the most common chromosomal abnormalities. It… …   Medical dictionary

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