Syndrome, Lennox-Gastaut
A severe form of epilepsy that usually begins in early childhood and is characterized by frequent seizures of multiple types, mental impairment, and a particular brain wave pattern (a slow spike-and-wave pattern). The seizures that are notoriously hard to treat and may lead to falls and injuries can be reduced in frequency by treatment with lamotrigine, a chemically novel antiepileptic drug. The syndrome is named for W.G. Lennox and H. Gastaut who described it. The Lennox-Gastaut syndrome usually develops in children between 1 and 8 years of age and is characterized by seizures, developmental delay, and behavioral disturbances such as poor social skills and attention-seeking behavior. Most children with it have impaired intellectual functioning or information processing. The disorder may be caused by brain injury, severe brain infections, genetic brain diseases, or developmental malformations of the brain. In some cases, no cause can be found. The types of seizures, which vary among Lennox-Gastaut patients, include tonic (stiffening of the body, upward deviation of the eyes, dilation of the pupils, and altered respiratory patterns), atonic (brief loss of muscle tone and consciousness, causing abrupt falls), atypical absence (staring spells), and myoclonic (sudden muscle jerks). There may be periods of frequent seizures mixed with brief, relatively seizure-free periods. The prognosis (outlook) for individuals with Lennox-Gastaut syndrome varies. There is no cure for the disorder. Complete recovery including freedom from seizures and normal development is very unusual.

Medical dictionary. 2011.

Look at other dictionaries:

  • Syndrome de lennox-gastaut — Le syndrome de Lennox Gastaut, également connu sous le nom de syndrome de Lennox, est une forme d épilepsie infantile difficile à traiter qui apparait le plus souvent entre l âge de 2 à 6 ans et est caractérisé par des crises fréquentes et de… …   Wikipédia en Français

  • Lennox-Gastaut syndrome — Infobox Disease Name = Lennox Gastaut syndrome ICD10 = ICD10|G|40|4|g|40 ICD9 = ICD9|345.0 eMedicineSubj = neuro eMedicineTopic = 186 DiseasesDB = 29493 Lennox Gastaut syndrome (LGS), also known as Lennox syndrome , is a difficult to treat form… …   Wikipedia

  • Lennox-Gastaut syndrome — A severe form of epilepsy that usually begins in early childhood and is characterized by frequent seizures of multiple types, mental impairment, and a particular brain wave pattern (a slow spike and wave pattern). The seizures that are… …   Medical dictionary

  • Lennox-Gastaut-Syndrom — Klassifikation nach ICD 10 G40.4 Sonstige generalisierte Epilepsie und epileptische Syndrome Lennox Syndrom …   Deutsch Wikipedia

  • Syndrome de Lennox-Gastaut — Le syndrome de Lennox Gastaut, également connu sous le nom de syndrome de Lennox, est une forme d épilepsie infantile difficile à traiter qui apparait le plus souvent entre l âge de 2 et 7 ans et qui se caractérise par des crises fréquentes et de …   Wikipédia en Français

  • Syndrome, Lennox — Also known as the Lennox Gastaut syndrome, a severe form of epilepsy that usually begins in early childhood and is characterized by frequent seizures of multiple types, mental impairment, and a particular brain wave pattern (a slow spike and wave …   Medical dictionary

  • Lennox-Gastaut syndrome — noun A difficult to treat form of childhood onset epilepsy, characterized by frequent seizures of different types and often accompanied by mental retardation and psychological and behavioural problems. Syn: LGS, Lennox syndrome …   Wiktionary

  • Síndrome Lennox-Gastaut — Clasificación y recursos externos CIE 10 G40.4 CIE 9 …   Wikipedia Español

  • Syndrome de west — Le syndrome de West, aussi connu sous le nom de spasmes infantiles, est une forme rare d épilepsie du nourrisson. Nommé d après le docteur anglais, William James West (1793 1848), qui le premier en a fait la description dans un article publié… …   Wikipédia en Français

  • Lennox — may refer to:*Lennox (district), an historic mormaerdom, earldom and then dukedom, in Stirling, Scotland *Lennox International, a global manufacturer of furnaces and central air conditioners.Other places around the world, named by Scottish… …   Wikipedia

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