Syndrome, locked-in
A neurological disorder characterized by complete paralysis of voluntary muscles in all parts of the body except for those that control eye movement. The locked-in syndrome is usually a complication of a cerebrovascular accident (a stroke) in the base of the pons in the brainstem. The patient is alert and fully conscious but cannot move. Only vertical movements of the eyes and blinking are possible. Locked-in syndrome can also be due to traumatic brain injury, demyelinating diseases (disorders in which the insulating material around brain cells is lost), and medication overdose. There is no cure for locked-in syndrome, nor is there a standard course of treatment. Functional neuromuscular stimulation may help activate some paralyzed muscles. Several devices to help communication are available. Other treatment is symptomatic and supportive. The prognosis for those with locked-in syndrome is poor. The majority of patients do not regain function.

Medical dictionary. 2011.

Look at other dictionaries:

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  • locked-in syndrome — noun (medicine) A neurological condition, resulting from brainstem damage, in which the subject is conscious and aware but unable to move or communicate, other than sometimes through blinking • • • Main Entry: ↑lock …   Useful english dictionary

  • Locked-In syndrome — Infobox Disease Name = PAGENAME Caption = Locked In syndrome can be caused by stroke at the level of the basilar artery denying blood to the pons, among other causes. DiseasesDB = ICD10 = ICD10|G|46|3|g|40 ICD9 = ICD9|344.81 ICDO = OMIM =… …   Wikipedia

  • Locked-in syndrome — A neurological disorder characterized by complete paralysis of voluntary muscles in all parts of the body except for those that control eye movement. The locked in syndrome is usually a complication of a cerebrovascular accident (a stroke) in the …   Medical dictionary

  • locked-in syndrome — (LOKT in sin.drohm, drum) n. A rare medical state in which the patient s brain stem has been destroyed, resulting in complete paralysis from the neck down while still maintaining full consciousness and mental activity. Example Citation: Jean… …   New words

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