T-cell receptor
A device used by T cells for recognizing specific antigens. T cells have receptors that are activated exclusively by a target antigen.

Medical dictionary. 2011.

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  • T cell receptor — proteinShort | Name = T cell receptor alpha locus caption = width = HGNCid = 12027 Symbol = TRA@ AltSymbols = TCRA EntrezGene = 6955 OMIM = 186880 RefSeq = UniProt = PDB = ECnumber = Chromosome = 14 Arm = q Band = 11.2 LocusSupplementaryData =… …   Wikipedia

  • T-cell receptor — Récepteur des cellules T Pour les articles homonymes, voir TCR. Le récepteur des cellules T ou TCR (de l’anglais T Cell receptor) est un complexe moléculaire qui se trouve sur la membrane des lymphocytes T (ou cellules T). Ce récepteur… …   Wikipédia en Français

  • T-cell receptor — The antigen recognising receptor on the surface of T cells. Heterodimeric (disulphide linked), one of the immunoglobulin superfamily of proteins; binds antigen in association with the major histocompatibility complex (MHC), leading to the… …   Dictionary of molecular biology

  • T cell receptor — An antigen binding protein, located on the surface of mammalian killer T cells, which mediates the cellular immune response. T cell antigen encoding genes are assembled from gene segments by somatic recombination processes that occur during… …   Glossary of Biotechnology

  • Artificial T cell receptor — Artificial T cell receptors (also known as chimeric T cell receptors) are engineered molecules, which when expressed by T cells, redirect the T cells to kill a target cell with a specificity dictated by the artificial receptor. [cite journal| url …   Wikipedia

  • T cell — T cells belong to a group of white blood cells known as lymphocytes, and play a central role in cell mediated immunity. They can be distinguished from other lymphocyte types, such as B cells and natural killer cells by the presence of a special… …   Wikipedia

  • T-cell large granular lymphocyte leukemia — Infobox Disease Name = PAGENAME Caption = DiseasesDB = ICD10 = ICD9 = ICDO = 9831/3 OMIM = MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = T cell large granular lymphocyte leukemia is a disease that exhibits an unexplained, chronic (> 6… …   Wikipedia

  • T cell antigen receptor — (TCR) the characteristic marker of T lymphocytes, consisting of two polypeptide chains linked by a disulfide bridge. Two forms exist: TCR 1, composed of α and β chains and occurring on helper and cytotoxic T cells, and the much less… …   Medical dictionary

  • T-cell antigen receptor — (TCR) The receptor on the T cell surface consisting of two antigen binding peptide chains; it is associated with a large number of other glycoproteins. Binding of antigen to the TCR, usually in association with MHC, activates the T cell …   Dictionary of microbiology

  • T cell — Immunol. any of several closely related lymphocytes, developed in the thymus, that circulate in the blood and lymph and orchestrate the immune system s response to infected or malignant cells, either by lymphokine secretions or by direct contact …   Universalium

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