granulocyte colony-stimulating factor

granulocyte colony-stimulating factor
granulocyte colony-stimulating factor n a colony-stimulating factor produced by macrophages, endothelial cells, and fibroblasts that acts to promote the maturation of precursor cells into granulocytes (as neutrophils) abbr. G-CSF see FILGRASTIM

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(G-CSF) a colony-stimulating factor, secreted by stimulated endothelial cells, fibroblasts, and macrophages, that stimulates the production of neutrophils from precursor cells. A recombinant form used therapeutically is called filgrastim.

Medical dictionary. 2011.

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  • Granulocyte colony-stimulating factor — Not to be confused with granulocyte macrophage colony stimulating factor. Colony stimulating factor 3 (granulocyte) Crystal structure of 3 molecules of human G CSF. From PDB …   Wikipedia

  • Granulocyte colony-stimulating factor receptor — The granulocyte colony stimulating factor receptor (G CSF R) also known as CD114 (Cluster of Differentiation 114), is a cell surface receptor for the granulocyte colony stimulating factor (G CSF).cite web | title = Entrez Gene: CSF3R colony… …   Wikipedia

  • granulocyte colony stimulating factor — См. macrophage colony stimulating factor …   Dictionary of molecular biology

  • granulocyte colony-stimulating factor — G CSF. A colony stimulating factor that stimulates the production of neutrophils (a type of white blood cell). It is a cytokine that is a type of hematopoietic (blood forming) agent. Also called G CSF and filgrastim …   English dictionary of cancer terms

  • granulocyte colony-stimulating factor — noun : a colony stimulating factor produced by macrophages, endothelial cells, and fibroblasts that acts to promote the maturation of precursor cells into granulocytes (as neutrophils) abbreviation G CSF …   Useful english dictionary

  • Colony-stimulating factor — Colony stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of hemopoietic stem cells, thereby activating intracellular signaling pathways that can cause the cells to proliferate and differentiate… …   Wikipedia

  • Granulocyte macrophage colony-stimulating factor receptor — The granulocyte macrophage colony stimulating factor receptor also known as CD116 (Cluster of Differentiation 116), is a receptor for granulocyte macrophage colony stimulating factor, which stimulates the production of white blood cells. The… …   Wikipedia

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  • Colony-stimulating factor — A laboratory made agent similar to a substance in the body that stimulates the production of blood cells. Treatment with colony stimulating factors (CSFs) can help the blood forming tissue recover from the effects of chemotherapy and radiation… …   Medical dictionary

  • colony-stimulating factor — A substance that stimulates the production of blood cells. Colony stimulating factors include granulocyte colony stimulating factor (G CSF), granulocyte macrophage colony stimulating factor (GM CSF), and promegapoietin …   English dictionary of cancer terms

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