Thrombotic thrombocytopenic purpura (TTP)

Thrombotic thrombocytopenic purpura (TTP)
A life-threatening disease involving embolism and thrombosis (plugging) of the small blood vessels in the brain. TTP is characterized by platelet microthrombi (tiny traveling clots composed of platelets, the clotting cells in the blood), thrombocytopenia (lack of platelets), hemolytic anemia (from the breakup of red blood cells), fever, renal (kidney) abnormalities and neurologic changes such as neurological signs such as aphasia, blindness, and convulsions. TTP is fortunately rare. It occurs at a rate of 3.7 cases per year per million persons. The mortality (death) rate for promptly treated cases ranges from 10 to 20 percent. Many drugs have been associated with TTP. One is the antiplatelet drug clopidogrel (Plavix).

Medical dictionary. 2011.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Thrombotic thrombocytopenic purpura — Classification and external resources Micrograph showing an advanced thrombotic microangiopathy, as may be seen in TTP. Kidney biopsy. PAS stain …   Wikipedia

  • thrombotic thrombocytopenic purpura — n hemolytic uremic syndrome that primarily affects adult females, is typically distinguished by only mild renal dysfunction but significant neurological deficits, and is marked by the presence of large aggregates of von Willebrand factor and a… …   Medical dictionary

  • thrombotic thrombocytopenic purpura — TTP a rare disorder of coagulation caused by deficiency of ADAMTS 13, a protein that is responsible for breaking down von Willebrand factor (see von Willebrand s disease). This results in haemolytic anaemia, thrombocytopenia, and fluctuating… …   The new mediacal dictionary

  • TTP (thrombotic thrombocytopenic purpura) — A life threatening disease involving embolism and thrombosis (plugging) of the small blood vessels in the brain. TTP is characterized by platelet microthrombi (tiny traveling clots composed of platelets, the clotting cells in the blood),… …   Medical dictionary

  • Purpura thrombotique thrombocytopénique — Classification internationale des maladies CIM 10 : M31.1 Le purpura thrombotique thrombocytopénique (PTT) ou maladie de Moschcowitz est une forme grave de microangiopathie thrombotique caractérisée par une anémie hémolytique par microangiopathie …   Wikipédia en Français

  • Purpura, thrombotic thrombocytopenic (TTP) — A life threatening disease involving embolism and thrombosis (plugging) of the small blood vessels in the brain. TTP is characterized by platelet microthrombi (tiny traveling clots composed of platelets, the clotting cells in the blood),… …   Medical dictionary

  • Purpura thrombotique thrombocytopenique — Purpura thrombotique thrombocytopénique Purpura thrombotique thrombocytopénique CIM 10 : M31.1 Le purpura thrombotique thrombocytopénique (PTT) ou maladie de Moschcowitz est une forme grave de microangiopathie thrombotique caractérisée par une… …   Wikipédia en Français

  • TTP — may refer to:* Thrombotic thrombocytopenic purpura, a blood disorder * Thymidine triphosphate, one of the four nucleoside triphosphates that make up DNA * Time to progression * Time Triggered Protocol, a concept related to networking * Titan… …   Wikipedia

  • TTP — Thrombotic Thrombocytopenic Purpura (Medical) **** To The Point (Internet » Chat) **** Trusted Third Party (Medical) **** Trusted Third Party (Computing » Networking) ** Tactics, Techniques, and Procedures (Governmental » Military) * Time… …   Abbreviations dictionary

  • TTP — Abbreviation for ribothymidine 5′ triphosphate. * * * thiamine triphosphate; thrombotic thrombocytopenic purpura; thymidine triphosphate; time to disease progression; time to peak; time to progression; tocopherol transfer protein; transtrabecular …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”