incomplete antibody

incomplete antibody
incomplete antibody n BLOCKING ANTIBODY

* * *

antibody that binds to erythrocytes or bacteria but does not produce agglutination; the nonagglutinating antibody is detectable with the antiglobulin (Coombs) test. For example, IgG anti-Rh antibodies do not agglutinate erythrocytes in physiologic saline whereas IgM antibodies do (the large IgM molecule can cross-link the erythrocytes at a wider separation so that there is less electrostatic repulsion due to the zeta potential). 2. a univalent antibody fragment, e.g., Fab fragment.

Medical dictionary. 2011.

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  • antibody — An immunoglobulin molecule produced by B lymphoid cells with a specific amino acid sequence evoked in humans or other animals by an antigen (immunogen). These molecules are characterized by reacting specifically with the antigen in some… …   Medical dictionary

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  • blocking antibody — n an antibody that combines with an antigen without visible reaction but prevents another antibody from later combining with or producing its usual effect on that antigen called also incomplete antibody * * * any antibody that by combining with… …   Medical dictionary

  • blocking antibody — noun : an antibody that combines with an antigen without producing visible reaction but preventing another antibody from later combining with or producing its usual effect on that antigen called also incomplete antibody, univalent antibody * * *… …   Useful english dictionary

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