Tophus
A nodular mass of uric acid crystals. Tophi are characteristically deposited in different soft tissue areas of the body in gout. The word tophus comes via Latin from the Greek tophos meaning a porous volcanic stone. In chronic (tophaceous) gout, nodular masses of uric acid crystals (tophi) deposit in different soft tissue areas of the body. Even though tophi are most commonly found as hard nodules around the fingers, at the tips of the elbows, and around the big toe, tophi nodules can appear anywhere in the body. They have been reported in unexpected areas such as in the ears, vocal cords, or around the spinal cord!
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1. See gouty t.. 2. A salivary calculus, or tartar. SYN: gouty pearl. [L. a calcareous deposit from springs, tufa]
- gouty t. a deposit of uric acid and urates in periarticular fibrous tissue, cartilage of the external ear, or kidney, in gout. SYN: arthritic calculus, uratoma.

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to·phus 'tō-fəs n, pl to·phi 'tō-.fī, -.fē a deposit of urates in tissues (as cartilage) characteristic of gout

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n. (pl. tophi)
a hard deposit of crystalline uric acid and its salts in the skin, cartilage (especially of the ears), or joints; a feature of gout.

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to·phus (toґfəs) pl. toґphi [L. “porous stone”] a chalky deposit of sodium urate occurring in gout; tophi form most often around joints in cartilage, bone, bursae, and subcutaneous tissue and in the external ear, producing a chronic, foreign-body inflammatory response.

Medical dictionary. 2011.

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  • tophus — [ tɔfys ] n. m. • 1765; tophe 1560; lat. tofus ou tophus → tuf ♦ Méd. Concrétion d urate de sodium ou de calcium qui se forme, chez les goutteux, aux articulations et parfois au bord du pavillon de l oreille. « la craie des tophus perçait partout …   Encyclopédie Universelle

  • Tophus — au niveau du coude chez un homme présentant une goutte chronique Un tophus tophi au pluriel est un dépôt sous cutané de cristaux d acide urique entouré de cellules inflammatoires. On les retrouve le plus souvent dans les ligaments et les tissus… …   Wikipédia en Français

  • Tophus — To phus, n.; pl. {Tophi}. [NL.: cf. F. tophus a mineral concretion in the joint. See {Toph}.] [Written also {tofus}.] 1. (Med.) One of the mineral concretions about the joints, and in other situations, occurring chiefly in gouty persons. They… …   The Collaborative International Dictionary of English

  • Tophus — Tophus, hartes Gewächs, meist kalkartiger Beschaffenheit, in den Sehnenscheiden, Gelenken u. an der Oberfläche der Knochen, meist Folge der Gicht od. Lustseuche. Tophi pulmonum, Knoten in den Lungen, von steinartiger, kalkartiger Beschaffenheit …   Pierer's Universal-Lexikon

  • tophus — [tō′fəs] n. pl. tophi [tō′fī] [L, tufa] Med. an abnormal mineral deposit, as of calcium carbonate, about the joints, on the roots of the teeth, etc., in a person who has the gout; chalkstone …   English World dictionary

  • Tophus — entzündliche Knotenbildung * * * Tophus   [lateinisch »Tuffstein«] der, /...phi, Medizin: entzündlicher Knoten, v. a. als Symptom der Gicht. * * * To|phus, der; , Tophi [lat. tophus, tofus = Tuffstein] (Med.): Knoten …   Universal-Lexikon

  • Tophus — To|phus der; , Tophi <aus lat. tofus, tophus »Tuff(stein)«> Knoten (meist entzündlicher Art; Med.); Tophus arthriticus [ ...kus]: Gichtknoten …   Das große Fremdwörterbuch

  • Tophus — A tophus (Latin: stone , plural tophi) is a deposit of crystallised monosodium urate in people with longstanding hyperuricemia. At this stage, most have already developed symptoms of the associated crystal arthopathy known as gout.Tophi form in… …   Wikipedia

  • tophus — tophaceous /teuh fay sheuhs/, adj. /toh feuhs/, n., pl. tophi / fuy/. Pathol. a calcareous concretion formed in the soft tissue about a joint, in the pinna of the ear, etc., esp. in gout; a gouty deposit. [1545 55; < L tophus, tofus TUFA] * * * …   Universalium

  • tophus — (to fus ) s. m. Terme de médecine. Dépôts de substance dure, comme osseuse, qui se forment soit dans l intérieur des organes, soit aux environs des articulations ; ils sont composés, dans le premier cas, de phosphate de chaux ; et, dans le second …   Dictionnaire de la Langue Française d'Émile Littré

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