Transaminase, serum glutamic oxaloacetic
An enzyme that is normally present in liver and heart cells, and is released into blood when the liver or heart is damaged. Blood SGOT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack). Some medications can also raise SGOT levels. Interpretation of elevated SGOT levels depends on the context, and can necessitate additional clinical and laboratory information. Also known as aspartate aminotransferase (AST).

Medical dictionary. 2011.

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  • serum glutamic-oxaloacetic transaminase — SGOT. An enzyme found in the liver, heart, and other tissues. A high level of serum glutamic oxaloacetic transaminase released into the blood may be a sign of liver or heart damage, cancer, or other diseases. Also called aspartate transaminase… …   English dictionary of cancer terms

  • serum glutamic oxaloacetic transaminase — noun An enzyme found in heart and liver tissues. Syn: aspartate transaminase, AST, aspartate aminotransferase …   Wiktionary

  • serum glutamic-oxaloacetic transaminase — SYN: aspartate aminotransferase …   Medical dictionary

  • serum glutamic oxaloacetic transaminase — SGOT …   The new mediacal dictionary

  • Глютаминовая Оксалоацетиновая Трансаминаза (Glutamic Oxaloacetic Transaminase, Got) — фермент, участвующий в процессе трансаминирования аминокислот. Этот фермент присутствует в сыворотке крови (serum GOT, SGOT); определение его содержания в сыворотке может быть полезным для диагностики острого инфаркта миокарда и острых… …   Медицинские термины

  • Serum — The clear liquid that can be separated from clotted blood. Serum differs from plasma, the liquid portion of normal unclotted blood containing the red and white cells and platelets. It is the clot that makes the difference between serum and plasma …   Medical dictionary

  • Transaminase clinical usage — Two of the better known enzymes in the transaminase class are serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT). Both SGOT and SGPT are normally found primarily in liver and heart cells, are released… …   Medical dictionary

  • Aspartate transaminase — Aspartate aminotransferase from Escherichia coli bound with cofactor pyridoxal 5 phosphate.[1] Identifiers …   Wikipedia

  • aspartate transaminase — An enzyme found in the liver, heart, and other tissues. A high level of aspartate transaminase released into the blood may be a sign of liver or heart damage, cancer, or other diseases. Also called serum glutamic oxaloacetic transaminase or SGOT …   English dictionary of cancer terms

  • aspartate transaminase — n ASPARTATE AMINOTRANSFERASE * * * (AST, ASAT) as·par·tate trans·am·i·nase (AST, ASAT) (ə spahrґtāt trans amґĭ nās) [EC 2.6.1.1] an enzyme of the transferase class that catalyzes the reversible transfer of an amino group from… …   Medical dictionary

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