myelin basic protein

myelin basic protein
myelin basic protein n a protein that is a constituent of myelin and is often found in higher than normal amounts in the cerebrospinal fluid of individuals affected with some demyelinating disease (as multiple sclerosis) abbr. MBP

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(MBP) a basic protein (MW 18,000) that constitutes about 30 per cent of myelin proteins; elevated levels of MBP occur in acute exacerbation of multiple sclerosis and acute cerebral infarction. Immunization of laboratory animals with MBP produces encephalomyelitis by inducing T cell activity that leads to demyelination and lymphoid infiltration. Called also encephalitogenic p.

Medical dictionary. 2011.

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  • Myelin basic protein — Rendering of MBP from PDB 1BX2 …   Wikipedia

  • Myelin basic protein — Das Myelin Basische Protein abgek. MBP, engl.: myelin basic protein ist ein Protein, das eine große Bedeutung für die Myelinscheide der Nervenzellen besitzt. Im Proteinanteil des Myelins macht es etwa 40 Prozent aus. In der Forschung über die… …   Deutsch Wikipedia

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  • myelin basic protein — noun : a protein that is a constituent of myelin and is often found in higher than normal amounts in the cerebrospinal fluid of individuals affected with some demyelinating diseases (as multiple sclerosis) …   Useful english dictionary

  • myelin basic protein — Major component of the myelin sheath in mammalian CNS. Used as an antigen will induce experimental allergic encephalitis, possibly a model for some neurodegenerative disorders …   Dictionary of molecular biology

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