nephrogenic diabetes insipidus

nephrogenic diabetes insipidus
nephrogenic diabetes insipidus n diabetes insipidus that is caused by partial or complete failure of the kidneys to respond to vasopressin

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diabetes insipidus caused by failure of the renal tubules to reabsorb water in response to antidiuretic hormone, without disturbance in the renal filtration and solute excretion rates; characterized by polyuria, extreme thirst, growth retardation, and developmental delay. The condition does not respond to exogenous vasopressin. It may be inherited as an X-linked trait or be acquired as a result of drug therapy or systemic disease.

Medical dictionary. 2011.

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