ornithine decarboxylase
ornithine decarboxylase n an enzyme that catalyzes the decarboxylation of ornithine to form putrescine

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or·ni·thine de·car·box·y·lase (orґnĭ-thēn de″kahr-bokґsə-lās) [EC 4.1.1.17] a cytosolic enzyme of the lyase class that catalyzes the decarboxylation of ornithine to form putrescine; the reaction occurs in the conversion of arginine to spermine and spermidine and in the synthesis of γ-aminobutyric acid via putrescine. The enzyme requires pyridoxal phosphate as a cofactor and is concentrated in rapidly proliferating cells.

Medical dictionary. 2011.

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  • ornithine — 2,5 Diaminovaleric acid; the l isomer is the amino acid formed when l arginine is hydrolyzed by arginase; not a constituent of proteins, but an important intermediate in the urea cycle; elevated levels seen in certain defects of the urea cycle. o …   Medical dictionary

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