Vitamin B3
Vitamin B3 is niacin. Deficiency of niacin causes pellagra. Pellagra was known as the "disease of the four D's" — dermatitis, diarrhea, dementia and death. The disease is specifically characterized by: Dermatitis: A rash on areas of the skin exposed to light or trauma and ulcerations within the mouth Diarrhea Dementia: Mental disorientation, confusion, delusions and depression Death, if untreated. Pellagra, once a puzzle, was solved by Joseph Goldberger (1874-1929). Serving in the Public Health Service, Dr. Goldberger proposed that pellagra was due to a nutritional deficiency and in 1915 began experiments with Mississippi prison inmates (who "volunteered" in return for full pardons). Dr. Goldberger fed them a poor diet he believed caused pellagra and within months, many developed the disease. Their symptoms of pellagra were reversed when meat, fresh vegetables and milk were added to their diet. Niacin, Dr. Goldberger subsequently showed, was the principle that had this remarkable effect. A readily-available B vitamin, niacin cures pellagra and prevents it. The name "pellagra" comes from the Italian "pelle", skin + "agra", rough = rough skin, referring to the skin problems in pellagra.

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vitamin B3 -'bē-'thrē n NIACIN

Medical dictionary. 2011.

Look at other dictionaries:

  • vitamin B3 — n. See {nicotinamide}. Syn: nicotinamide. [PJC] …   The Collaborative International Dictionary of English

  • Vitamin B3 — Strukturformel Allgemeines Trivialname Vitamin B3 Vitamin B5 (seltene Bezeichnung) Andere Namen …   Deutsch Wikipedia

  • vitamin B3 — niacinamide iacinamide n. The amide of niacin (nicotinic acid), called also {nicotinamide}. It was at one time called {vitamin B3}, and can function to relieve nicotinic acid deficiency. Chemical formula {C6H6N2O}, chemically it is 3… …   The Collaborative International Dictionary of English

  • vitamin B3 — See nicotinic acid. * * * …   Universalium

  • vitamin B3 — noun niacin …   Wiktionary

  • Vitamin B3 — Niacin; PP Faktor; Nicotinsäure …   Universal-Lexikon

  • vitamin B3 — See nicotinic acid …   Useful english dictionary

  • Vitamin-B — ist eine Vitamin Gruppe, in der acht wasserlösliche Vitamine zusammengefasst sind, die alle als Vorstufen für Koenzyme dienen. Die Nummerierung ist nicht durchgehend, weil sich bei vielen Substanzen, die ursprünglich als Vitamine galten, der… …   Deutsch Wikipedia

  • Vitamin B — ist eine Vitamin Gruppe, in der acht Vitamine zusammengefasst sind, die alle als Vorstufen für Koenzyme dienen. Die Nummerierung ist nicht durchgehend, weil sich bei vielen Substanzen, die ursprünglich als Vitamine galten, der Vitamin Charakter… …   Deutsch Wikipedia

  • Vitamin A — is retinol. Carotene compounds (found, for example, in egg yolk, butter and cream) are gradually converted by the body to vitamin A (retinol). A form of vitamin A called retinal is responsible for transmitting light sensation in the retina of the …   Medical dictionary

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