restriction fragment length polymorphism

restriction fragment length polymorphism
restriction fragment length polymorphism n variation in the length of a restriction fragment produced by a specific restriction enzyme acting on DNA from different individuals that usu. results from a genetic mutation (as an insertion or deletion) and that may be used as a genetic marker called also RFLP

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(RFLP) a genetic polymorphism in DNA sequence that can be detected on the basis of differences in DNA fragment lengths produced by digestion with a specific restriction endonuclease.

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  • Restriction Fragment Length Polymorphism — n. The older and more discriminating form of DNA testing. Restriction Fragment Length Polymorphism is a process that breaks DNA strands into tiny fragments at specific points on the DNA chain. Also known as HLA DQ Alpha, or simply DQ Alpha.… …   Law dictionary

  • restriction fragment length polymorphism — restriction fragment length polymorphism. См. ПДРФ. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Restriction fragment length polymorphism — A Restriction fragment length polymorphism (or RFLP, often pronounced as rif lip ) is a variation in the DNA sequence of a genome that can be detected by breaking the DNA into pieces with restriction enzymes and analyzing the size of the… …   Wikipedia

  • Restriction Fragment Length Polymorphism — Restriktionsfragmentlängenpolymorphismus, abgekürzt RFLP (sprich: Riflip , von engl.: Restriction Fragment Length Polymorphism, auch PLP: PCR Längen Polymorphismus) bezeichnet Unterschiede von DNA Sequenzen homologer Chromosomen, welche als… …   Deutsch Wikipedia

  • Terminal restriction fragment length polymorphism — (TRFLP or sometimes T RFLP) is a molecular biology technique for profiling of microbial communities based on the position of a restriction site closest to a labeled end of an amplified gene. The method is based on digesting a mixture of PCR… …   Wikipedia

  • restriction fragment length polymorphism — (RFLP)    The different length fragments of DNA produced by the action of a restriction enzyme at a specific polymorphic site. If the restriction endonuclease recognizes the variable site, then two fragments are produced; if not, only one is… …   Forensic science glossary

  • restriction fragment length polymorphism — Abbreviation: RFLP A class of genetic marker based on the detection of variation in the length of restriction fragments generated when DNA is treated with restriction endonucleases. Differences in fragment lengths arise due to genetic variation… …   Glossary of Biotechnology

  • restriction fragment length polymorphism — noun Date: 1982 variation in the length of a DNA fragment produced by a specific restriction enzyme acting on DNA from different individuals that usually results from a genetic mutation and that may be used as a genetic marker …   New Collegiate Dictionary

  • restriction fragment length polymorphism — noun : variation in the length of a DNA fragment produced by a specific restriction enzyme acting on DNA from different individuals that usually results from a genetic mutation (as an insertion or deletion) and that may be used as a genetic… …   Useful english dictionary

  • restriction fragment length polymorphism — (= RFLP) Technique, also known as DNA fingerprinting, that allows familial relationships to be established by comparing the characteristic polymorphic patterns that are obtained when certain regions of genomic DNA are amplified (typically by PCR) …   Dictionary of molecular biology

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