subacute sclerosing panencephalitis

subacute sclerosing panencephalitis
subacute sclerosing panencephalitis n a usu. fatal neurological disease of children and young adults that is caused by infection of the brain by a previously latent morbillivirus causing measles and that is marked esp. by behavioral changes, myoclonic seizures, progressive deterioration of motor and mental functioning, and coma abbr. SSPE

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(SSPE) a rare and devastating form of leukoencephalitis usually affecting children and adolescents. Insidious in onset, it characteristically produces progressive cerebral dysfunction over several weeks or months and death within a year. There is also demyelination with intranuclear inclusion bodies in nerve cells and oligodendroglia. High titers of measles virus in the serum and cerebrospinal fluid have indicated a linkage between this condition and earlier measles infection. Called also Dawson encephalitis, subacute inclusion body encephalitis, subacute sclerosing leukoencephalopathy, van Bogaert encephalitis, and van Bogaert sclerosing leukoencephalitis.

Medical dictionary. 2011.

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  • Subacute sclerosing panencephalitis — Classification and external resources ICD 10 A81.1 ICD 9 046.2 …   Wikipedia

  • subacute sclerosing panencephalitis — noun a rare chronic progressive encephalitis caused by the measles virus and occurring primarily in children and young adults; death usually occurs within three years; characterized by primary measles infection before the age of two years • Syn:… …   Useful english dictionary

  • subacute sclerosing panencephalitis — noun Etymology: panencephalitis from New Latin, from pan + encephalitis Date: 1950 a usually fatal neurological disease of children and young adults caused by infection of the brain by a previously latent measles virus that is marked especially… …   New Collegiate Dictionary

  • subacute sclerosing leukoencephalopathy — subacute sclerosing panencephalitis …   Medical dictionary

  • subacute sclerosing panencephalitis — Diffuse inflammation of the brain resulting from virus and prion infections …   Dictionary of microbiology

  • subacute sclerosing panencephalitis — (= SSPE) Chronic progressive illness seen in children a few years after measles infection, and involving demyelination of the cerebral cortex. Virus apparently persists in brain cells: usually considered a slow virus disease …   Dictionary of molecular biology

  • subacute sclerosing panencephalitis — /skli roh sing pan en sef euh luy tis, pan /, Pathol. a rare infection of the central nervous system caused by the measles virus, occurring in children and adolescents several years after a measles attack and characterized by progressive… …   Universalium

  • subacute sclerosing panencephalitis — (SSPE) a rare and late complication of measles characterized by a slow progressive neurological deterioration that is usually fatal. It can occur four to ten years after the initial infection …   Medical dictionary

  • subacute sclerosing panencephalitis — SSPE a rare and late complication of measles characterized by a slow progressive neurological deterioration that is usually fatal. It can occur four to ten years after the initial infection …   The new mediacal dictionary

  • subacute sclerosing panencephalitis — sub′acute scle•ros′ing pan′en•ceph•a•li′tis [[t]sklɪˈroʊ sɪŋ ˈpæn ɛnˌsɛf əˈlaɪ tɪs, ˌpæn [/t]] n. pat an infection of the central nervous system caused by the measles virus, occurring in children and adolescents several years after a measles… …   From formal English to slang

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