tamoxifen

tamoxifen
ta·mox·i·fen ta-'mäk-si-.fen n a selective estrogen receptor modulator that acts as an estrogen antagonist in breast tissue and is administered orally in the form of its citrate C26H29NO·C6H8O7 esp. to treat breast cancer see NOLVADEX

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n.
a drug used in the treatment of breast cancer: it combines with hormone receptors in the tumour to inhibit the effect of oestrogens (see anti-oestrogen). Side-effects include nausea, vaginal bleeding, facial flushing, tumour pain, and hypercalcaemia. Tamoxifen is being investigated for its effects in preventing breast cancer in those women considered to be at risk of developing the disease. Trade name: Nolvadex.

Medical dictionary. 2011.

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  • Tamoxifen — Systematic (IUPAC) name (Z …   Wikipedia

  • tamoxifen — fármaco prototipo de los modulares de los receptores estrogénicos empleado en el tratamiento de los tumores de mama ER positivos estructura química [véase http://www.iqb.es/diccio/t/ta.htm#tamoxifen] monografía [véase… …   Diccionario médico

  • tamoxifen — [tə mäk′sə fen΄] n. a synthetic hormone, C32H37NO10, used as an estrogen blocking drug to inhibit the growth of certain types of tumors, esp. in cases of advanced breast cancer: in full tamoxifen citrate …   English World dictionary

  • Tamoxifen — Ta*mox i*fen (t[a^]*m[o^]k s[i^]*f[e^]n), n. a chemical compound ({C26H29NO}) which is non steroidal but physiogically active as an estrogen antagonist. It is used to treat postmenopausal breast cancer. Chemically it is 1 p… …   The Collaborative International Dictionary of English

  • Tamoxifen — Strukturformel Allgemeines Freiname Tamoxifen …   Deutsch Wikipedia

  • tamoxifen — /teuh mok seuh feuhn, fen /, n. Pharm. an antineoplastic drug, C26H29NO, that blocks the estrogen receptors on cancer cells, used in the treatment of breast cancer. [1970 75; perh. T(RANS) + AM(INO) + OXY 2 + PHEN(YL), with resp. of y and ph] * * …   Universalium

  • tamoxifen — A drug used to treat certain types of breast cancer in women and men. It is also used to prevent breast cancer in women who have had ductal carcinoma in situ (abnormal cells in the ducts of the breast) and are at a high risk of developing breast… …   English dictionary of cancer terms

  • tamoxifen — [[t]təmɒ̱ksɪfen[/t]] N UNCOUNT Tamoxifen is a drug that is used for treating women who have breast cancer …   English dictionary

  • tamoxifen — n. a drug used in the treatment of breast cancer: it binds with hormone receptors in the tumour to inhibit the effect of oestrogens (see anti oestrogen, selective oestrogen receptor modulator). Tamoxifen is also used to treat female infertility… …   The new mediacal dictionary

  • tamoxifen citrate — A synthetic nonsteroidal estrogen antagonist used in the prevention and treatment of breast cancer.By competing with naturally occurring estrogen for binding sites on tissue cells, tamoxifen inhibits the stimulant effect of estrogen on …   Medical dictionary

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