acantholysis
Separation of individual epidermal keratinocytes from their neighbor, as in conditions such as pemphigus vulgaris and Darier disease. [acantho- + G. lysis, loosening]

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ac·an·thol·y·sis .ak-.an-'thäl-ə-səs, .ā-.kan-, .ak-ən- n, pl -y·ses -ə-.sēz atrophy of the stratum spinosum of the epidermis

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acan·thol·y·sis (ak″an-tholґĭ-sis) [acantho- + -lysis] disruption of the intercellular connections between keratinocytes of the epidermis. A primary type is caused by lysis of intercellular cement substance, and secondary types occur with conditions such as types of pemphigus or dyskeratosis. There is often secondary disruption of desmosomes, as well as a defined sequence of cellular degenerative events. acantholytic adj

Medical dictionary. 2011.

Look at other dictionaries:

  • Acantholysis — vgl. Akantholyse …   Das Wörterbuch medizinischer Fachausdrücke

  • Acantholysis — Infobox Disease Name = PAGENAME Caption = DiseasesDB = ICD10 = ICD9 = ICD9|701.8 ICDO = OMIM = MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = D000051 Acantholysis is a separation of individual epidermal keratinocytes from their neighbor …   Wikipedia

  • acantholysis — noun The loss of intercellular connections, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris …   Wiktionary

  • acantholysis — ac·an·thol·y·sis …   English syllables

  • acantholysis — noun a breakdown of a cell layer in the epidermis (as in pemphigus) • Hypernyms: ↑skin disease, ↑disease of the skin, ↑skin disorder • Part Holonyms: ↑pemphigus …   Useful english dictionary

  • ACANTHOLYSIS BULLOSA — ACANTHOLYSIS BULLOSA, см. Epider molysis bullosa …   Большая медицинская энциклопедия

  • акантолиз — (acantholysis; аканто + греч. lysis разрушение, растворение) дегенеративное изменение шиповатого слоя эпидермиса, проявляющееся разрушением межклеточных мостиков, потерей клетками большей части цитоплазмы и морфологическими изменениями ядер;… …   Большой медицинский словарь

  • Аканто́лиз — (acantholysis; Аканто + греч. lysis разрушение, растворение) дегенеративное изменение шиповатого слоя эпидермиса, проявляющееся разрушением межклеточных мостиков, потерей клетками большей части цитоплазмы и морфологическими изменениями ядер;… …   Медицинская энциклопедия

  • Pemphigus — Classification and external resources ICD 10 L10 ICD …   Wikipedia

  • Pemphigoid — Classification and external resources ICD 10 L12 ICD 9 694.5 …   Wikipedia

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