transforming growth factor
- transforming growth factor
transforming growth factor n any of a group of polypeptides that are secreted by a variety of cells (as monocytes, T cells, or blood platelets) and have diverse effects (as inducing angiogenesis, stimulating fibroblast proliferation, or inhibiting T cell proliferation) on the division and activity of cells
abbr. TGF
* * *
(TGF) either of two types of proteins secreted by transformed cells and stimulating growth of normal cells, although not causing transformation. TGF-α binds the epidermal growth factor receptor and also stimulates growth of microvascular endothelial cells. TGF-β comprises several proteins, which are found in hematopoietic tissue, stimulate wound healing, and in vitro are antagonists of lymphopoiesis and myelopoiesis. Similar proteins involved in inducing the change of undifferentiated tissues into specific types of tissues, including bone morphogenetic proteins, activins, and inhibins, are said to belong to the superfamily of TGF-β proteins.
Medical dictionary.
2011.
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Transforming growth factor — (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGF beta;. The name Transforming Growth Factor is somewhat arbitrary, since the two classes of TGFs are not… … Wikipedia
Transforming Growth Factor — Le TGF ou Transforming growth factor est une cytokine polypeptidique qui est classé en deux groupes : le TGFα, produit par les macrophages, les neurones et les kératinocytes, est un facteur de développement cellulaire et le TGFβ qui agit… … Wikipédia en Français
Transforming growth factor — Der Transforming Growth Factor (Abk. TGF, deut. Transformierender Wachstumsfaktor) gehört zu den Zytokinen zählenden Signalmolekülen. Sie sind namensgebend für die TGF Signalwege. TGF spielen eine sehr wichtige Rolle bei der embryonalen… … Deutsch Wikipedia
Transforming Growth Factor — Der Transforming Growth Factor (Abk. TGF, deut. Transformierender Wachstumsfaktor) gehört zu den Zytokinen zählenden Signalmolekülen. Sie sind namensgebend für die TGF Signalwege. TGF spielen eine sehr wichtige Rolle bei der embryonalen… … Deutsch Wikipedia
Transforming growth factor — Le TGF ou transforming growth factor est une cytokine polypeptidique qui est classé en deux groupes : le TGFα, produit par les macrophages, les neurones et les kératinocytes, est un facteur de développement cellulaire et le TGFβ qui agit… … Wikipédia en Français
Transforming growth factor, beta 3 — Transforming growth factor, beta 3, also known as TGFB3, is a human gene.cite web | title = Entrez Gene: TGFB3 transforming growth factor, beta 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=7043|… … Wikipedia
Transforming growth factor beta superfamily — Pfam box Symbol = TGF beta Name = Transforming growth factor beta like domain width = caption = Pfam= PF00019 InterPro= IPR001839 SMART= PROSITE= PDOC00223 SCOP = 1tfg TCDB = OPM family= OPM protein= PDB=PDB3|1ktzA:312 412 PDB3|1tgjA:312 412… … Wikipedia
transforming growth factor — Proteins secreted by transformed cells that can stimulate growth of normal cells. Unfortunate misnomer, since they induce aspects of transformed phenotype, such as growth in semi solid agar, but do not actually transform. TGF a, a 50 amino acid… … Dictionary of molecular biology
transforming growth factor — noun : any of a group of polypeptides that are secreted by a variety of cells (as monocytes, T cells, or blood platelets) and have diverse effects (as inducing angiogenesis, stimulating fibroblast proliferation, or inhibiting T cell… … Useful english dictionary
Growth factor — Dieser Artikel behandelt Wachstumsfaktor als Begriff aus der Biologie. Das Wort wird außerdem verwendet bei der mathematischen Untersuchung von Wachstumsprozessen (siehe Wachstumsfaktor (Mathematik)) Als Wachstumsfaktoren werden Proteine… … Deutsch Wikipedia
