trastuzumab

trastuzumab
tras·tu·zu·mab .tras-'tü-zü-.mab n a genetically engineered monoclonal antibody that is administered by injection to slow or inhibit tumor growth in some advanced breast cancers by blocking a cell membrane receptor which receives signals promoting cancer cell growth see herceptin

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n.
a monoclonal antibody used to treat types of breast cancer that are positive for HER2: the drug binds to these receptors on the tumour. It is administered by intravenous infusion; side-effects include chills, fever, and allergic reactions. Trade name: Herceptin.

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tras·tuz·u·mab (tras-tuzґu-mab) a recombinant DNA-derived humanized monoclonal antibody that binds to human growth factor receptor 2 (HER2), a protein overexpressed in some breast cancers; used as an antineoplastic in the treatment of metastatic breast cancer with overexpression of HER2, administered intravenously.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Trastuzumab — Nombre (IUPAC) sistemático trastuzumab Identificadores …   Wikipedia Español

  • Trastuzumab — Masse/Länge Primärstruktur 145,5 kDa …   Deutsch Wikipedia

  • Trastuzumab — Herceptin Fab Général No CAS …   Wikipédia en Français

  • trastuzumab — /tra stooˈzū mab/ noun A therapeutic antibody used in the treatment of advanced breast cancer ORIGIN: tras (arbitrary syllable), tumour, zu (denoting a humanized antibody), and monoclonal antibody …   Useful english dictionary

  • Trastuzumab — drugbox type = mab | source = Humanized | | target = HER2 | | width = 300 | CAS number = 180288 69 1 | ATC prefix = L | ATC suffix =01XC03 | ATC supplemental =| PubChem = | DrugBank = BTD00098 | C=6470 | H=10012 | N=1726 | O=2013 | S=42 |… …   Wikipedia

  • trastuzumab — A monoclonal antibody that binds to HER2 (human epidermal growth factor receptor), and can kill HER2 positive cancer cells. Monoclonal antibodies are made in the laboratory and can locate and bind to cancer cells. Trastuzumab is used to treat… …   English dictionary of cancer terms

  • trastuzumab — noun A drug used in the treatment of breast cancer which targets the HER 2 oncogene. Syn: Herceptin …   Wiktionary

  • trastuzumab — n. a monoclonal antibody used to treat types of breast cancer that are positive for HER2: the drug binds to these receptors on the tumour. It is administered by intravenous infusion; side effects include chills, fever, and allergic reactions.… …   The new mediacal dictionary

  • Herceptin — Trastuzumab Größe 145,5 kDa Bezeichner Externe IDs CAS …   Deutsch Wikipedia

  • 180288-69-1 — Trastuzumab Trastuzumab Herceptin Fab Général No CAS …   Wikipédia en Français

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