acetyl-CoA
Condensation product of coenzyme A and acetic acid, symbolized as CoAS∼COCH3; intermediate in transfer of two-carbon fragment, notably in its entrance into the tricarboxylic acid cycle and in fatty acid synthesis. SYN: acetyl-coenzyme A, active acetate.
- acetyl-CoA acetyltransferase an acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis. SYN: acetoacetyl-CoA thiolase, acetyl-CoA thiolase, thiolase.
- acetyl-CoA acylase SYN: acetyl-CoA hydrolase.
- acetyl-CoA acyltransferase an enzyme catalyzing the thioclastic cleavage by coenzyme A of β-ketoacyl-CoA, forming an acyl-CoA with a carbon chain shorter by two atoms, the missing two atoms appearing as acetyl-CoA. A step in fatty acid degradation. SEE ALSO: acetyl-CoA acetyltransferase. SYN: 3-ketoacyl-CoA thiolase, β-ketothiolase.
- acetyl-CoA carboxylase a ligase that catalyzes the reaction of acetyl-CoA, CO2, H2O, and ATP, with a divalent cation as catalyst and covalently bound biotin, to form malonyl-CoA, ADP, and Pi (or the reverse decarboxylase); N-carboxybiotin is an intermediate. A crucial enzyme in fatty acid synthesis.
- acetyl-CoA deacylase SYN: acetyl-CoA hydrolase.
- acetyl-CoA:α-glucosaminide acetyltransferase an enzyme involved in the synthesis of certain carbohydrate moieties on proteins. A deficiency of this enzyme leads to mucopolysaccharidosis type III C.
- acetyl-CoA hydrolase a hydrolase that cleaves acetate and coenzyme A from acetyl-CoA. SYN: acetyl-CoA acylase, acetyl-CoA deacylase.
- acetyl-CoA ligase a ligase that catalyzes the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA. A key step in the activation of acetate. SYN: acetate thiokinase, acetate-CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase.
- acetyl-CoA synthetase SYN: acetyl-CoA ligase.
- acetyl-CoA thiolase SYN: acetyl-CoA acetyltransferase.
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acetyl coenzyme A

Medical dictionary. 2011.

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  • Acétyl-CoA — Acétyl coenzyme A L acétyl coenzyme A (acétyl coA ou acétyl CoA), molécule à haut potentiel d hydrolyse est au centre d un carrefour métabolique. En tant qu il peut être lié à la dégradation du pyruvate, soit être le résultat de la beta oxydation …   Wikipédia en Français

  • acetyl CoA — kō ā n ACETYL COENZYME A * * * ac·e·tyl CoA (asґə təl) (as″ə tēlґ ko aґ) acetyl coenzyme A …   Medical dictionary

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  • Acetyl-CoA — Strukturmodell des Coenzym A. Strukturformel von Coenzym A. Coenzym A (auch Koenzym A, kurz CoA oder CoASH) ist ein Coenzym, das zur „Aktivierung“ von Alkansäuren und deren …   Deutsch Wikipedia

  • acetyl-CoA — • acetyl coenzyme A …   Dictionary of medical acronyms & abbreviations

  • acetyl coA — ə¦sēd.əlˌkōˈā; ¦asəd.əl , əˌtēl noun Usage: usually capitalized C Etymology: acetyl coenzyme A : acetyl coenzyme A …   Useful english dictionary

  • acetyl CoA — noun Date: 1951 acetyl coenzyme A …   New Collegiate Dictionary

  • acetyl-coA — a·ce·tyl co·A (ə sētʹl kōʹāʹ, ăs ĭ tl ) n. See acetyl coenzyme A. * * * …   Universalium

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