5HT1 agonist

5HT1 agonist
any one of a class of drugs that stimulate serotonin receptors and are effective in the treatment of migraine by rapidly reversing the dilatation of blood vessels in the head that causes the migraine headache. The group includes almotriptan (Almogran), naratriptan (Naramig), sumatriptan, and zolmitriptan (Zomig).

Medical dictionary. 2011.

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  • 5HT1 agonist — triptan any one of a class of drugs that stimulate serotonin (5 hydroxytryptamine) receptors and are effective in the relief of migraine headaches by causing constriction of cerebral blood vessels. The group includes almotriptan (Almogran),… …   The new mediacal dictionary

  • zolmitriptan — zol·mi·trip·tan .zōl mi trip .tan n a triptan C16H21N3O2 administered orally to treat migraine headaches * * * n. see 5HT1 agonist * * * zol·mi·trip·tan (zōl″mĭ tripґtan) a selective serotonin receptor agonist used to relieve… …   Medical dictionary

  • ergotamine — C33H35N5O5; an alkaloid from ergot, used for the relief of migraine; it is a potent stimulant of smooth muscle, particularly of the blood vessel s and the uterus, and produces adrenergic blockade (chiefly of the …   Medical dictionary

  • serotonin — A vasoconstrictor, liberated by blood platelets, that inhibits gastric secretion and stimulates smooth muscle; present in relatively high concentrations in some areas of the central nervous system (hypothalamus, basal ganglia), and occurring in… …   Medical dictionary

  • sumatriptan — su·ma·trip·tan .sü mə trip .tan, tən n a triptan C14H21N3O2S that is administered as a nasal spray or in the form of its succinate C14H21N3O2S·C4H6O4 either as an oral tablet or by injection and that is used in the treatment of migraine attacks * …   Medical dictionary

  • almotriptan — n. see 5HT1 agonist …   Medical dictionary

  • naratriptan — n. see 5HT1 agonist …   Medical dictionary

  • almotriptan — n.; see 5HT1 agonist …   The new mediacal dictionary

  • naratriptan — n.; see 5HT1 agonist …   The new mediacal dictionary

  • serotonin — 5 hydroxytryptamine; n. a compound widely distributed in the tissues, particularly in the blood platelets, intestinal wall, and central nervous system. Serotonin is thought to play a role in inflammation similar to that of histamine and it is… …   The new mediacal dictionary

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