alkylating agents
a class of drugs used in chemotherapy that includes cyclophosphamide and melphalan. These drugs bind to DNA and prevent complete separation of the two DNA chains during cell division.

Medical dictionary. 2011.

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  • alkylating agents — a class of drugs used in chemotherapy that includes cyclophosphamide and melphalan. These drugs bind to DNA and prevent complete separation of the two DNA chains during cell division. Side effects are those of other cytotoxic drugs; in addition,… …   The new mediacal dictionary

  • Агенты Алкилирующие (Alkylating Agents) — класс лекарственных препаратов, используемых при химиотерапии (например, циклофосфамид и мелфалан). Эти лекарственные вещества связываются с молекулами ДНК и предотвращают полное отделение двух цепей молекул ДНК друг от друга в процессе деления… …   Медицинские термины

  • alkylating agent — n a substance that causes replacement of hydrogen by an alkyl group esp. in a biologically important molecule specif one with mutagenic activity that inhibits cell division and growth and is used to treat some cancers * * * a highly reactive… …   Medical dictionary

  • Alkylating antineoplastic agent — An alkylating antineoplastic agent is an alkylating agent that attaches an alkyl group to DNA.Since cancer cells generally proliferate unrestrictively more than healthy cells do, cancer cells are more sensitive to DNA damage such as being… …   Wikipedia

  • List of chemotherapeutic agents — This is a list of specific that are known to be of use in the treatment of cancer, otherwise known as . This list is organized by type of agent, though the subsections are not necessarily definitive and are subject to revision. Each drug is… …   Wikipedia

  • Alkylation — Alkylating agent redirects here. For the class of drugs, see alkylating antineoplastic agent. Alkylation is the transfer of an alkyl group from one molecule to another. The alkyl group may be transferred as an alkyl carbocation, a free radical, a …   Wikipedia

  • nitrosourea — Alkylating agent used in the treatment of many neoplasms; an example is BCNU [N,N′ bis(2 chloroethyl) N n.; carmustine]. * * * ni·tro·so·urea yu̇ rē ə n any of a group of lipid soluble drugs that function as alkylating agents, have the ability to …   Medical dictionary

  • АГЕНТЫ АЛКИЛИРУЮЩИЕ — (alkylating agents) класс лекарственных препаратов, используемых при химиотерапии (например, циклофосфамид и мелфалан). Эти лекарственные вещества связываются с молекулами ДНК и предотвращают полное отделение двух цепей молекул ДНК друг от друга… …   Толковый словарь по медицине

  • Chemotherapy — A woman being treated with docetaxel chemotherapy for breast cancer. Cold mittens and wine coolers are placed on her hands and feet to reduce harm to her nails. Chemotherapy (sometimes cancer chemotherapy) is the treatment of cancer with an… …   Wikipedia

  • drug — drug1 /drug/, n., v., drugged, drugging. n. 1. Pharm. a chemical substance used in the treatment, cure, prevention, or diagnosis of disease or used to otherwise enhance physical or mental well being. 2. (in federal law) a. any substance… …   Universalium

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